Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β

Heavy alcohol consumption is a known risk factor for various forms of dementia and the development of Alzheimer’s disease (AD). In this work, we investigated how intragastric alcohol feeding may alter the liver-to-brain axis to induce and/or promote AD pathology. Four weeks of intragastric alcohol f...

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Detalles Bibliográficos
Autores principales: Garcia, Jerome, Chang, Rudy, Steinberg, Ross A., Arce, Aldo, Yang, Joshua, Van Der Eb, Peter, Abdullah, Tamara, Chandrashekar, Devaraj V., Eck, Sydney M., Meza, Pablo, Liu, Zhang-Xu, Cadenas, Enrique, Cribbs, David H., Kaplowitz, Neil, Sumbria, Rachita K., Han, Derick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520570/
https://www.ncbi.nlm.nih.gov/pubmed/36187787
http://dx.doi.org/10.3389/fphys.2022.930402

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