Cargando…

Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)

BACKGROUND: Stroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood. OBJECTIVE: The aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days...

Descripción completa

Detalles Bibliográficos
Autores principales: dos Santos, Emily, Wollmann, Giulia M., Nagel, Vivian, Ponte, Herminia M. S., Furtado, Luis E. T. A., Martins-Filho, Rui K. V., Weiss, Gustavo, Martins, Sheila C. O., Ferreira, Leslie E., de França, Paulo H. C., Cabral, Norberto L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520622/
https://www.ncbi.nlm.nih.gov/pubmed/36188387
http://dx.doi.org/10.3389/fneur.2022.966785
_version_ 1784799666152407040
author dos Santos, Emily
Wollmann, Giulia M.
Nagel, Vivian
Ponte, Herminia M. S.
Furtado, Luis E. T. A.
Martins-Filho, Rui K. V.
Weiss, Gustavo
Martins, Sheila C. O.
Ferreira, Leslie E.
de França, Paulo H. C.
Cabral, Norberto L.
author_facet dos Santos, Emily
Wollmann, Giulia M.
Nagel, Vivian
Ponte, Herminia M. S.
Furtado, Luis E. T. A.
Martins-Filho, Rui K. V.
Weiss, Gustavo
Martins, Sheila C. O.
Ferreira, Leslie E.
de França, Paulo H. C.
Cabral, Norberto L.
author_sort dos Santos, Emily
collection PubMed
description BACKGROUND: Stroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood. OBJECTIVE: The aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days post-stroke in the cities of different Brazilian macro-regions. METHODS: This is an observational, prospective, and population-based study, led in Canoas (South), Joinville (South, reference center), Sertãozinho (Southeast), and Sobral (Northeast) in Brazil. It was developed according to the three-step criteria recommended by the World Health Organization to conduct population-based studies on stroke. Using different sources, all hospitalized and ambulatory patients with stroke were identified and the same criteria were kept in all cities. All first events were included, regardless of sex, age, or type of stroke. Demographic and risk factor data were collected, followed by biochemical, electrocardiographic, and radiological test results. Functional status and lethality were obtained using the mRankin scale through telephonic interview (validated Brazilian version). RESULTS: In 1 year, 932 stroke cases were registered (784 ischemic stroke, 105 hemorrhagic stroke, and 43 subarachnoid hemorrhage). The incidence rates per 100,000 inhabitants, adjusted for the world population, were 63 in Canoas, 106 in Joinville, 72 in Sertãozinho, and 96 in Sobral. The majority (70.8%) were followed for 90 days. Kaplan–Meier curves showed that 90-day survival was different among cities. Sobral, which has the lowest socioeconomic indexes, revealed the worst results in terms of lethality and functional status. CONCLUSION: This study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location.
format Online
Article
Text
id pubmed-9520622
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-95206222022-09-30 Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) dos Santos, Emily Wollmann, Giulia M. Nagel, Vivian Ponte, Herminia M. S. Furtado, Luis E. T. A. Martins-Filho, Rui K. V. Weiss, Gustavo Martins, Sheila C. O. Ferreira, Leslie E. de França, Paulo H. C. Cabral, Norberto L. Front Neurol Neurology BACKGROUND: Stroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood. OBJECTIVE: The aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days post-stroke in the cities of different Brazilian macro-regions. METHODS: This is an observational, prospective, and population-based study, led in Canoas (South), Joinville (South, reference center), Sertãozinho (Southeast), and Sobral (Northeast) in Brazil. It was developed according to the three-step criteria recommended by the World Health Organization to conduct population-based studies on stroke. Using different sources, all hospitalized and ambulatory patients with stroke were identified and the same criteria were kept in all cities. All first events were included, regardless of sex, age, or type of stroke. Demographic and risk factor data were collected, followed by biochemical, electrocardiographic, and radiological test results. Functional status and lethality were obtained using the mRankin scale through telephonic interview (validated Brazilian version). RESULTS: In 1 year, 932 stroke cases were registered (784 ischemic stroke, 105 hemorrhagic stroke, and 43 subarachnoid hemorrhage). The incidence rates per 100,000 inhabitants, adjusted for the world population, were 63 in Canoas, 106 in Joinville, 72 in Sertãozinho, and 96 in Sobral. The majority (70.8%) were followed for 90 days. Kaplan–Meier curves showed that 90-day survival was different among cities. Sobral, which has the lowest socioeconomic indexes, revealed the worst results in terms of lethality and functional status. CONCLUSION: This study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location. Frontiers Media S.A. 2022-09-15 /pmc/articles/PMC9520622/ /pubmed/36188387 http://dx.doi.org/10.3389/fneur.2022.966785 Text en Copyright © 2022 Santos, Wollmann, Nagel, Ponte, Furtado, Martins-Filho, Weiss, Martins, Ferreira, França and Cabral. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
dos Santos, Emily
Wollmann, Giulia M.
Nagel, Vivian
Ponte, Herminia M. S.
Furtado, Luis E. T. A.
Martins-Filho, Rui K. V.
Weiss, Gustavo
Martins, Sheila C. O.
Ferreira, Leslie E.
de França, Paulo H. C.
Cabral, Norberto L.
Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
title Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
title_full Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
title_fullStr Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
title_full_unstemmed Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
title_short Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
title_sort incidence, lethality, and post-stroke functional status in different brazilian macro-regions: the samba study (analysis of stroke in multiple brazilian areas)
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520622/
https://www.ncbi.nlm.nih.gov/pubmed/36188387
http://dx.doi.org/10.3389/fneur.2022.966785
work_keys_str_mv AT dossantosemily incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT wollmanngiuliam incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT nagelvivian incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT ponteherminiams incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT furtadoluiseta incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT martinsfilhoruikv incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT weissgustavo incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT martinssheilaco incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT ferreiralesliee incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT defrancapaulohc incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas
AT cabralnorbertol incidencelethalityandpoststrokefunctionalstatusindifferentbrazilianmacroregionsthesambastudyanalysisofstrokeinmultiplebrazilianareas