Regulation of CYP450 and drug transporter mediated by gut microbiota under high-altitude hypoxia

Hypoxia, an essential feature of high-altitude environments, has a significant effect on drug metabolism. The hypoxia–gut microbiota–CYP450/drug transporter axis is emerging as a vital factor in drug metabolism. However, the mechanisms through which the gut microbiota mediates the regulation of CYP4...

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Detalles Bibliográficos
Autores principales: Bai, Xue, Yang, Jianxin, Liu, Guiqin, Zhu, Junbo, Wang, Qian, Gu, Wenqi, La, Linli, Li, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520702/
https://www.ncbi.nlm.nih.gov/pubmed/36188572
http://dx.doi.org/10.3389/fphar.2022.977370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520702/
https://www.ncbi.nlm.nih.gov/pubmed/36188572
http://dx.doi.org/10.3389/fphar.2022.977370

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