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Regulation of CYP450 and drug transporter mediated by gut microbiota under high-altitude hypoxia
Hypoxia, an essential feature of high-altitude environments, has a significant effect on drug metabolism. The hypoxia–gut microbiota–CYP450/drug transporter axis is emerging as a vital factor in drug metabolism. However, the mechanisms through which the gut microbiota mediates the regulation of CYP4...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520702/ https://www.ncbi.nlm.nih.gov/pubmed/36188572 http://dx.doi.org/10.3389/fphar.2022.977370 |