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Chemo- and Stereoselective Synthesis of Substituted Thiazoles from tert-Alcohols Bearing Alkene and Alkyne Groups with Alkaline Earth Catalysts

[Image: see text] We report here that thioamides can distinguish C–C double bonds and C–C triple bonds chemoselectively when subjected to a reaction with pent-1-en-4-yn-3-ol derivatives in the presence of Ca(OTf)(2). This protocol offers a fast, efficient, and high-yielding synthesis of functionaliz...

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Detalles Bibliográficos
Autores principales: Yaragorla, Srinivasarao, Latha, Dandugula Sneha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520744/
https://www.ncbi.nlm.nih.gov/pubmed/36188313
http://dx.doi.org/10.1021/acsomega.2c05085