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Everolimus pharmacokinetics and exposure-response relationship in Japanese patients with advanced breast cancer

Background: Everolimus is one of the key drugs for the treatment of advanced breast cancer. The optimal target concentration range for everolimus therapy in patients with breast cancer has not yet been established. This study aimed to characterize everolimus pharmacokinetics (PK) and determine the r...

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Detalles Bibliográficos
Autores principales: Hirabatake, Masaki, Mizuno, Tomoyuki, Kato, Hironori, Hashida, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520775/
https://www.ncbi.nlm.nih.gov/pubmed/36188563
http://dx.doi.org/10.3389/fphar.2022.984002