APA-Scan: detection and visualization of 3′-UTR alternative polyadenylation with RNA-seq and 3′-end-seq data

BACKGROUND: The eukaryotic genome is capable of producing multiple isoforms from a gene by alternative polyadenylation (APA) during pre-mRNA processing. APA in the 3′-untranslated region (3′-UTR) of mRNA produces transcripts with shorter or longer 3′-UTR. Often, 3′-UTR serves as a binding platform f...

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Detalles Bibliográficos
Autores principales: Fahmi, Naima Ahmed, Ahmed, Khandakar Tanvir, Chang, Jae-Woong, Nassereddeen, Heba, Fan, Deliang, Yong, Jeongsik, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520800/
https://www.ncbi.nlm.nih.gov/pubmed/36171568
http://dx.doi.org/10.1186/s12859-022-04939-w

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