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Three-dimensional nuclear telomere architecture and differential expression of aurora kinase genes in chronic myeloid leukemia to measure cell transformation

BACKGROUND: Telomere dysfunction results in aneuploidy, and ongoing chromosomal abnormalities. The three-dimensional (3D) nuclear organization of telomeres allows for a distinction between normal and tumor cells. On the other hand, aurora kinase genes (AURKA and AURKB) play an important role regulat...

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Detalles Bibliográficos
Autores principales:	de Oliveira, Fábio Morato, Jamur, Valderez Ravaglio, Merfort, Lismeri Wuicik, Pozzo, Aline Rangel, Mai, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520804/ https://www.ncbi.nlm.nih.gov/pubmed/36175852 http://dx.doi.org/10.1186/s12885-022-10094-5

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