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Metformin regulates multiple signaling pathways within castration-resistant human prostate cancer cells

BACKGROUND: The biguanide metformin has been shown to not only reduce circulating glucose levels but also suppress in vitro and in vivo growth of prostate cancer. However, the mechanisms underlying the anti-tumor effects of metformin in advanced prostate cancers are not fully understood. The goal of...

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Detalles Bibliográficos
Autores principales: Olokpa, Emuejevoke, Mandape, Sammed N., Pratap, Siddharth, Stewart, La Monica V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520831/
https://www.ncbi.nlm.nih.gov/pubmed/36175875
http://dx.doi.org/10.1186/s12885-022-10115-3