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Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca(2+) axis

BACKGROUND: Microglia pyroptosis-mediated neuroinflammation is thought to be the crucial pathogenesis of sepsis-associated encephalopathy (SAE). Erbin has been reported to be associated with various inflammatory diseases. However, the role of Erbin in SAE and the relationship between Erbin and micro...

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Detalles Bibliográficos
Autores principales: Jing, Guoqing, Zuo, Jing, Fang, Qing, Yuan, Min, Xia, Yun, Jin, Qiyan, Liu, Yuping, Wang, Yanlin, Zhang, Zongze, Liu, Wanhong, Wu, Xiaojing, Song, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520943/
https://www.ncbi.nlm.nih.gov/pubmed/36171629
http://dx.doi.org/10.1186/s12974-022-02598-5