Erbin protects against sepsis-associated encephalopathy by attenuating microglia pyroptosis via IRE1α/Xbp1s-Ca(2+) axis

BACKGROUND: Microglia pyroptosis-mediated neuroinflammation is thought to be the crucial pathogenesis of sepsis-associated encephalopathy (SAE). Erbin has been reported to be associated with various inflammatory diseases. However, the role of Erbin in SAE and the relationship between Erbin and micro...

Descripción completa

Detalles Bibliográficos
Autores principales: Jing, Guoqing, Zuo, Jing, Fang, Qing, Yuan, Min, Xia, Yun, Jin, Qiyan, Liu, Yuping, Wang, Yanlin, Zhang, Zongze, Liu, Wanhong, Wu, Xiaojing, Song, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520943/
https://www.ncbi.nlm.nih.gov/pubmed/36171629
http://dx.doi.org/10.1186/s12974-022-02598-5

Ejemplares similares

Ejemplares similares