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Clinical implication of minimal residual disease assessment by next-generation sequencing-based immunoglobulin clonality assay in pediatric B-acute lymphoblastic leukemia

Measuring minimal residual disease (MRD) during treatment is valuable to identify acute lymphoblastic leukemia (ALL) patients who require intensified treatment to avert relapse. We performed the next-generation sequencing (NGS)-based immunoglobulin gene (Ig) clonality assay and evaluated its clinica...

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Detalles Bibliográficos
Autores principales:	Lee, Jae Wook, Kim, Yonggoo, Ahn, Ari, Lee, Jong Mi, Yoo, Jae Won, Kim, Seongkoo, Cho, Bin, Chung, Nack-Gyun, Kim, Myungshin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521036/ https://www.ncbi.nlm.nih.gov/pubmed/36185293 http://dx.doi.org/10.3389/fonc.2022.957743

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