Cargando…

Iron- and erythropoietin-resistant anemia in a spontaneous breast cancer mouse model

Anemia of cancer (AoC) with its multifactorial etiology and complex pathology is a poor prognostic indicator for cancer patients. One of the main causes of AoC is cancer-associated inflammation that activates mechanisms, commonly observed in anemia of inflammation, whereby functional iron deficiency...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bregolat, Nuria Fabregas, Ruetten, Maja, da Silva, Milene Costa, Aboouf, Mostafa A., Ademi, Hyrije, von Büren, Nadine, Armbruster, Julia, Stirn, Martina, Altamura, Sandro, Marques, Oriana, Rodriguez, Josep M. Monné, Samillan, Victor J., Singh, Rashim Pal, Wielockx, Ben, Muckenthaler, Martina U., Gassmann, Max, Thiersch, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2022
Materias:	Article - Platelet Biology & its Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521231/ https://www.ncbi.nlm.nih.gov/pubmed/35385924 http://dx.doi.org/10.3324/haematol.2022.280732

Ejemplares similares

Erythropoietin receptor regulates tumor mitochondrial biogenesis through iNOS and pAKT
por: Aboouf, Mostafa A., et al.
Publicado: (2022)

Voluntary exercise does not always suppress lung cancer progression
por: Leimbacher, Aurelia C., et al.
Publicado: (2023)

Sorting nexin 24 is required for α-granule biogenesis and cargo delivery in megakaryocytes
por: Lacey, Joanne, et al.
Publicado: (2022)

Iron Regulation in Elderly Asian Elephants (Elephas maximus) Chronically Infected With Mycobacterium tuberculosis
por: Ruetten, Maja, et al.
Publicado: (2020)

Establishment of a Bernard-Soulier syndrome model in zebrafish
por: Lin, Qing, et al.
Publicado: (2021)

Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo
por: Nicolai, Leo, et al.
Publicado: (2021)

Platelet dysfunction in platelet-type von Willebrand disease due to the constitutive triggering of the Lyn-PECAM1 inhibitory pathway
por: Bury, Loredana, et al.
Publicado: (2021)

Antiplatelet antibody predicts platelet desialylation and apoptosis in immune thrombocytopenia
por: Zheng, Shiying Silvia, et al.
Publicado: (2022)

Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets
por: Wolf, Robert, et al.
Publicado: (2022)

The deglycosylated form of 1E12 inhibits platelet activation and prothrombotic effects induced by VITT antibodies
por: Vayne, Caroline, et al.
Publicado: (2022)

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets
por: van Osch, Thijs L.J., et al.
Publicado: (2022)

Enhancing regulatory T-cell function via inhibition of high mobility group box 1 protein signaling in immune thrombocytopenia
por: Wang, Haoyi, et al.
Publicado: (2022)

Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen
por: Simeone, Paola, et al.
Publicado: (2022)

Immune-mediated thrombotic thrombocytopenic purpura plasma induces calcium- and IgG-dependent endothelial activation: correlations with disease severity
por: Tellier, Edwige, et al.
Publicado: (2022)

Exome sequencing in 116 patients with inherited thrombocytopenia that remained of unknown origin after systematic phenotype-driven diagnostic workup
por: Marconi, Caterina, et al.
Publicado: (2022)

Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia
por: Capaci, Valeria, et al.
Publicado: (2022)

Targeting a thrombopoietin-independent strategy in the discovery of a novel inducer of megakaryocytopoiesis, DMAG, for the treatment of thrombocytopenia
por: Wang, Long, et al.
Publicado: (2022)

Adolescents and young adults with newly diagnosed primary immune thrombocytopenia
por: Schifferli, Alexandra, et al.
Publicado: (2023)

Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
por: Jacobs, Robert A., et al.
Publicado: (2021)

Complement protein C3a enhances adaptive immune responses towards FVIII products
por: Ringler, Eva, et al.
Publicado: (2023)

Mean platelet size related to glycoprotein-specific autoantibodies and platelet-associated IgG
por: JAVELA, K, et al.
Publicado: (2007)

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2
por: HUGHES, C E, et al.
Publicado: (2008)

Non-genomic effects of PPARγ ligands: inhibition of GPVI-stimulated platelet activation
por: Moraes, L A, et al.
Publicado: (2010)

Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells
por: Moraes, L A, et al.
Publicado: (2010)

The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function
por: Holbrook, L-M, et al.
Publicado: (2012)

CLEC‐2‐dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP
por: Borgognone, A., et al.
Publicado: (2014)

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis
por: UNSWORTH, A J, et al.
Publicado: (2012)

Manipulating megakaryocytes to manufacture platelets ex vivo
por: Karagiannis, P, et al.
Publicado: (2015)

Akt and mitogen‐activated protein kinase enhance C‐type lectin‐like receptor 2‐mediated platelet activation by inhibition of glycogen synthase kinase 3α/β
por: Moroi, A. J., et al.
Publicado: (2015)

Modified platelet deposition on matrix metalloproteinase 13 digested collagen I
por: Howes, J.‐M., et al.
Publicado: (2015)

The role of ADAMTS‐13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies
por: Phillips, E. H., et al.
Publicado: (2016)

Amplification of human platelet activation by surface pannexin-1 channels
por: Taylor, K A, et al.
Publicado: (2014)

Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6
por: van den Bosch, M T J, et al.
Publicado: (2014)

Protein kinase C and P2Y(12) take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets
por: Moore, S F, et al.
Publicado: (2014)

Use of next‐generation sequencing and candidate gene analysis to identify underlying defects in patients with inherited platelet function disorders
por: Leo, V. C., et al.
Publicado: (2015)

Circulating primers enhance platelet function and induce resistance to antiplatelet therapy
por: Blair, T A, et al.
Publicado: (2015)

Super‐resolution microscopy as a potential approach to diagnosis of platelet granule disorders
por: Westmoreland, D., et al.
Publicado: (2016)

Increased expression of HIF2α during iron deficiency–associated megakaryocytic differentiation
por: Jimenez, K., et al.
Publicado: (2015)

Platelet collagen receptor Glycoprotein VI‐dimer recognizes fibrinogen and fibrin through their D‐domains, contributing to platelet adhesion and activation during thrombus formation
por: Induruwa, I., et al.
Publicado: (2018)

A humanized monoclonal antibody that inhibits platelet‐surface ERp72 reveals a role for ERp72 in thrombosis
por: Holbrook, L.‐M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6goualanc56pl7q81lhic01fg0