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Genomic determinants impacting the clinical outcome of mogamulizumab treatment for adult T-cell leukemia/lymphoma

In order to identify genomic biomarkers for the outcome of mogamulizumab-containing treatment, an integrated molecular analysis of adult T-cell leukemia/lymphoma (ATL) was conducted on 64 mogamulizumab-naïve patients. Among driver genes, CCR4 and CCR7 alterations were observed in 22% and 11% of the...

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Detalles Bibliográficos
Autores principales:	Tanaka, Norio, Mori, Seiichi, Kiyotani, Kazuma, Ota, Yuki, Gotoh, Osamu, Kusumoto, Shigeru, Nakano, Nobuaki, Suehiro, Youko, Ito, Asahi, Choi, Ilseung, Ohtsuka, Eiichi, Hidaka, Michihiro, Nosaka, Kisato, Yoshimitsu, Makoto, Imaizumi, Yoshitaka, Iida, Shinsuke, Utsunomiya, Atae, Noda, Tetsuo, Nishikawa, Hiroyoshi, Ueda, Ryuzo, Ishida, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2022
Materias:	Article - Non-Hodgkin Lymphoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521232/ https://www.ncbi.nlm.nih.gov/pubmed/35417939 http://dx.doi.org/10.3324/haematol.2021.280352

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