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Preclinical evaluation and structural optimization of anti-BCMA CAR to target multiple myeloma
Chimeric antigen receptor (CAR) T-cell based immunotherapy has become a promising treatment mainly for hematological malignancies. Following the major success of CD19-targeted CAR, new potential targets for other malignancies are required. As such, B-cell maturation antigen (BCMA) is an attractive t...
Autores principales: | Harush, Ortal, Asherie, Nathalie, Kfir-Erenfeld, Shlomit, Adler, Galit, Barliya, Tilda, Assayag, Miri, Gatt, Moshe E., Stepensky, Polina, Cohen, Cyrille J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521250/ https://www.ncbi.nlm.nih.gov/pubmed/35354252 http://dx.doi.org/10.3324/haematol.2021.280169 |
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