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The glycolytic enzyme PFKFB3 determines bone marrow endothelial progenitor cell damage after chemotherapy and irradiation

Bone marrow (BM) endothelial progenitor cell (EPC) damage of unknown mechanism delays the repair of endothelial cells (EC) and recovery of hematopoiesis after chemo-radiotherapy. We found increased levels of the glycolytic enzyme PFKFB3 in the damaged BM EPC of patients with poor graft function, a c...

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Detalles Bibliográficos
Autores principales: Lyu, Zhong-Shi, Tang, Shu-Qian, Xing, Tong, Zhou, Yang, Lv, Meng, Fu, Hai-Xia, Wang, Yu, Xu, Lan-Ping, Zhang, Xiao-Hui, Lee, Hsiang-Ying, Kong, Yuan, Huang, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521251/
https://www.ncbi.nlm.nih.gov/pubmed/35354250
http://dx.doi.org/10.3324/haematol.2021.279756

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