Cargando…

Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments

Background: Knee osteoarthritis (KOA), a chronic degenerative disease, is mainly characterized by destruction of articular cartilage and inflammatory reactions. At present, there is a lack of economical and effective clinical treatment. Zhuifeng Tougu (ZFTG) capsules have been clinically approved fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Xiaotong, Li, Naping, Wu, Yongrong, Yan, Ke, Mi, Yilin, Yi, Nanxing, Tan, Xuyi, Kuang, Gaoyan, Lu, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521277/ https://www.ncbi.nlm.nih.gov/pubmed/36188596 http://dx.doi.org/10.3389/fphar.2022.951860

Ejemplares similares

Baicalein Alleviates Osteoarthritis Progression in Mice by Protecting Subchondral Bone and Suppressing Chondrocyte Apoptosis Based on Network Pharmacology
por: Yi, Nanxing, et al.
Publicado: (2022)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

Heparin alleviates LPS-induced endothelial injury by regulating the TLR4/MyD88 signaling pathway
por: Liu, Wenxun, et al.
Publicado: (2021)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway
por: Tang, Hui, et al.
Publicado: (2023)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

Tougu Xiaotong capsule exerts a therapeutic effect by improving knee meniscus in the early osteoarthritis rat model
por: Wu, Guangwen, et al.
Publicado: (2020)

A MyD88 meddles with survival
por: Bashyam, Hema
Publicado: (2007)

Role of MyD88 in Adenovirus Keratitis
por: Zhou, Xiaohong, et al.
Publicado: (2016)

Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
por: Kim, Ki Hyung, et al.
Publicado: (2012)

TLR4/MyD88 signaling determines the metastatic potential of breast cancer cells
por: Wu, Kunlin, et al.
Publicado: (2018)

TLR/MyD88-mediated Innate Immunity in Intestinal Graft-versus-Host Disease
por: Lee, Young-Kwan, et al.
Publicado: (2017)

Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling
por: Wu, Li-Rong, et al.
Publicado: (2017)

Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora
por: Zhan, Lianghui, et al.
Publicado: (2022)

Fuzi-Lizhong Decoction Alleviates Nonalcoholic Fatty Liver Disease by Blocking TLR4/MyD88/TRAF6 Signaling
por: Yang, Jiayao, et al.
Publicado: (2022)

MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis
por: Yang, Du-Jiang, et al.
Publicado: (2022)

MyD88 contribution to ocular surface homeostasis
por: Reins, Rose Y., et al.
Publicado: (2017)

Mechanism of MyD88S mediated signal termination
por: Pustelny, Katarzyna, et al.
Publicado: (2022)

A Novel Kindred with MyD88 Deficiency
por: Bucciol, Giorgia, et al.
Publicado: (2022)

Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway
por: Sun, Xiujiang, et al.
Publicado: (2021)

l-Isoleucine Administration Alleviates DSS-Induced Colitis by Regulating TLR4/MyD88/NF-κB Pathway in Rats
por: Mao, Xiangbing, et al.
Publicado: (2022)

Mycobacterium tuberculosis Subverts the TLR-2 - MyD88 Pathway to Facilitate Its Translocation into the Cytosol
por: Rahman, Md. Aejazur, et al.
Publicado: (2014)

IRAK4 inhibition to shut down TLR signaling in autoimmunity and MyD88-dependent lymphomas
por: Küppers, Ralf
Publicado: (2015)

Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways
por: Pang, Zheng, et al.
Publicado: (2018)

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology
por: Rangasamy, Suresh B., et al.
Publicado: (2018)

Enhanced Calvarial Bone Healing in CD11c-TLR4(−/−) and MyD88(−/−) Mice
por: Wang, Dan, et al.
Publicado: (2017)

The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer
por: Bates, Mark, et al.
Publicado: (2020)

Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils
por: Müller, Beate J., et al.
Publicado: (2021)

Data on Tougu Xiaotong capsules may inhibit p38 MAPK pathway-mediated inflammation in vitro
por: Li, Xihai, et al.
Publicado: (2019)

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
por: Livraghi-Butrico, Alessandra, et al.
Publicado: (2012)

TLR2 and TLR4 Mediate Differential Responses to Limb Ischemia through MyD88-Dependent and Independent Pathways
por: Sachdev, Ulka, et al.
Publicado: (2012)

TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury
por: Hussain, Salik, et al.
Publicado: (2020)

In vivo and in vitro studies of Danzhi Jiangtang capsules against diabetic cardiomyopathy via TLR4/MyD88/NF-κB signaling pathway
por: Shi, Hui, et al.
Publicado: (2021)

The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice
por: de Vos, Alex F., et al.
Publicado: (2015)

Hyaluronan Signaling during Ozone-Induced Lung Injury Requires TLR4, MyD88, and TIRAP
por: Li, Zhuowei, et al.
Publicado: (2011)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_88v4cqvklpuahhp2nfk248fr44