Replication of a synthetic oligomer using chameleon base-pairs

Salt bridges were used to attach polymerisable amidine monomers to an oligomeric benzoic acid template. CuAAC oligomerisation reactions in the presence of a benzoic acid 3-mer template gave the amidine 3-mer copy as the major product. Cleavage of ester linkers was used to hydrolyse off the amidine r...

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Detalles Bibliográficos
Autores principales: Núñez-Villanueva, Diego, Hunter, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521413/
https://www.ncbi.nlm.nih.gov/pubmed/36094173
http://dx.doi.org/10.1039/d2cc04580j
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author Núñez-Villanueva, Diego
Hunter, Christopher A.
author_facet Núñez-Villanueva, Diego
Hunter, Christopher A.
author_sort Núñez-Villanueva, Diego
collection PubMed
description Salt bridges were used to attach polymerisable amidine monomers to an oligomeric benzoic acid template. CuAAC oligomerisation reactions in the presence of a benzoic acid 3-mer template gave the amidine 3-mer copy as the major product. Cleavage of ester linkers was used to hydrolyse off the amidine recognition units and convert the product into a benzoic acid 3-mer copy of the original template.
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spelling pubmed-95214132022-10-31 Replication of a synthetic oligomer using chameleon base-pairs Núñez-Villanueva, Diego Hunter, Christopher A. Chem Commun (Camb) Chemistry Salt bridges were used to attach polymerisable amidine monomers to an oligomeric benzoic acid template. CuAAC oligomerisation reactions in the presence of a benzoic acid 3-mer template gave the amidine 3-mer copy as the major product. Cleavage of ester linkers was used to hydrolyse off the amidine recognition units and convert the product into a benzoic acid 3-mer copy of the original template. The Royal Society of Chemistry 2022-09-12 /pmc/articles/PMC9521413/ /pubmed/36094173 http://dx.doi.org/10.1039/d2cc04580j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Núñez-Villanueva, Diego
Hunter, Christopher A.
Replication of a synthetic oligomer using chameleon base-pairs
title Replication of a synthetic oligomer using chameleon base-pairs
title_full Replication of a synthetic oligomer using chameleon base-pairs
title_fullStr Replication of a synthetic oligomer using chameleon base-pairs
title_full_unstemmed Replication of a synthetic oligomer using chameleon base-pairs
title_short Replication of a synthetic oligomer using chameleon base-pairs
title_sort replication of a synthetic oligomer using chameleon base-pairs
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521413/
https://www.ncbi.nlm.nih.gov/pubmed/36094173
http://dx.doi.org/10.1039/d2cc04580j
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