Using In Silico Bioinformatics Algorithms for the Accurate Prediction of the Impact of Spike Protein Mutations on the Pathogenicity, Stability, and Functionality of the SARS-CoV-2 Virus and Analysis of Potential Therapeutic Targets

Coronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have used bioinformatics to investigate seventeen mutations in the spike protein of SARS-CoV-2, as this mediates infection of human cells and is the target of most vaccine strategies and antibody-b...

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Detalles Bibliográficos
Autores principales: Alizadehmohajer, Negin, Zahedifar, Shahrzad, Sohrabi, Ehsan, Shaddel Basir, Sedighe, Nourigheimasi, Shima, Falak, Reza, Nedaeinia, Reza, A. Ferns, Gordon, Emami Nejad, Asieh, Manian, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521556/
https://www.ncbi.nlm.nih.gov/pubmed/36173498
http://dx.doi.org/10.1007/s10528-022-10282-9

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