Cargando…

Epigenetic modifications: Critical participants of the PD-L1 regulatory mechanism in solid tumors (Review)

Immune checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) axis have achieved marked and durable efficacy in patients with different solid tumors and have improved their survival. However, the presence of primary or acquired resistance to immu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Xiaoran, Wu, Jibiao, Wang, Bin, Liu, Cun, Liu, Lijuan, Sun, Changgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521627/ https://www.ncbi.nlm.nih.gov/pubmed/36129152 http://dx.doi.org/10.3892/ijo.2022.5424

Ejemplares similares

Determination of Genetic and Epigenetic Modifications-Related Prognostic Biomarkers of Breast Cancer: Genome High-Throughput Data Analysis
por: Gao, Chundi, et al.
Publicado: (2021)

Natural Polysaccharides and Their Derivates: A Promising Natural Adjuvant for Tumor Immunotherapy
por: Li, Ye, et al.
Publicado: (2021)

ADRB1 was identified as a potential biomarker for breast cancer by the co-analysis of tumor mutational burden and immune infiltration
por: Wang, Jia, et al.
Publicado: (2020)

Post-Translational Modifications of cGAS-STING: A Critical Switch for Immune Regulation
por: Yu, Yang, et al.
Publicado: (2022)

Role of macrophages in tumor progression and therapy (Review)
por: Xu, Yiwei, et al.
Publicado: (2022)

PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy
por: Liu, Jinhua, et al.
Publicado: (2021)

Deciphering of Key Pharmacological Pathways of Poria Cocos Intervention in Breast Cancer Based on Integrated Pharmacological Method
por: Ma, Xiaoran, et al.
Publicado: (2020)

Tumor accomplice: T cell exhaustion induced by chronic inflammation
por: Fang, Liguang, et al.
Publicado: (2022)

Crosstalk and plasticity driving between cancer-associated fibroblasts and tumor microenvironment: significance of breast cancer metastasis
por: Zhang, Wenfeng, et al.
Publicado: (2023)

Development of a risk scoring system for evaluating the prognosis of patients with Her2-positive breast cancer
por: Gao, Chundi, et al.
Publicado: (2020)

Epigenetic Modification of PD-1/PD-L1-Mediated Cancer Immunotherapy against Melanoma
por: Nanamori, Hikaru, et al.
Publicado: (2022)

Identifying the Effect of Ursolic Acid Against Triple-Negative Breast Cancer: Coupling Network Pharmacology With Experiments Verification
por: Zhang, Yubao, et al.
Publicado: (2021)

Construction and Analysis of Competing Endogenous RNA Networks for Breast Cancer Based on TCGA Dataset
por: Wang, Xue, et al.
Publicado: (2020)

Integrative transcriptome data mining for identification of core lncRNAs in breast cancer
por: Zhang, Xiaoming, et al.
Publicado: (2019)

Subtype Classification, Immune Infiltration, and Prognosis Analysis of Lung Adenocarcinoma Based on Pyroptosis-Related Genes
por: Liu, Qi, et al.
Publicado: (2022)

Identifying Regulatory Posttranslational Modifications of PD-L1: A Focus on Monoubiquitinaton
por: Horita, Henrick, et al.
Publicado: (2017)

Roles of tumor-associated macrophages in anti-PD-1/PD-L1 immunotherapy for solid cancers
por: Zhang, Hao, et al.
Publicado: (2023)

Remodeling the Epigenetic Landscape of Cancer—Application Potential of Flavonoids in the Prevention and Treatment of Cancer
por: Jiang, Weiyi, et al.
Publicado: (2021)

Prognostic significance of PD-L1 in solid tumor: An updated meta-analysis
por: Wang, Qianqian, et al.
Publicado: (2017)

Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking
por: Li, Jie, et al.
Publicado: (2018)

The Mechanism of Quercetin in the Treatment of Lung Squamous Cell Carcinoma Based on a Protein-Protein Interaction Network
por: Lu, Yiping, et al.
Publicado: (2022)

PD-1/PD-L1 immune checkpoint inhibitors in neoadjuvant therapy for solid tumors (Review)
por: Tang, Quanying, et al.
Publicado: (2023)

Tumor Characterization in Breast Cancer Identifies Immune-Relevant Gene Signatures Associated With Prognosis
por: Li, Jie, et al.
Publicado: (2019)

PD-L1 and Survival in Solid Tumors: A Meta-Analysis
por: Wu, Pin, et al.
Publicado: (2015)

Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis
por: Weng, Yi Ming, et al.
Publicado: (2018)

Recursive Motif Analyses Identify Brain Epigenetic Transcription Regulatory Modules
por: Banerjee, Sharmi, et al.
Publicado: (2019)

Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond
por: Breiling, Achim, et al.
Publicado: (2015)

Regulation of Intrinsic Functions of PD-L1 by Post-Translational Modification in Tumors
por: Nihira, Naoe Taira, et al.
Publicado: (2022)

Regulation of post-translational modification of PD-L1 and advances in tumor immunotherapy
por: Feng, Chong, et al.
Publicado: (2023)

Tumor Mutation Burden and Immune Invasion Characteristics in Triple Negative Breast Cancer: Genome High-Throughput Data Analysis
por: Gao, Chundi, et al.
Publicado: (2021)

Prognostic value of PD –L1 expression in patients with primary solid tumors
por: Xiang, Xiao, et al.
Publicado: (2017)

Combinatorial regimens of chemotherapeutic agents: A new perspective on raising the heat of the tumor immune microenvironment
por: Liu, Jingyang, et al.
Publicado: (2022)

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
por: Darvin, Pramod, et al.
Publicado: (2019)

Clinical observation of the efficacy of PD‐1/PD‐L1 inhibitors in the treatment of patients with advanced solid tumors
por: Wang, Miao, et al.
Publicado: (2021)

Development and validation of an integrative pan-solid tumor predictor of PD-1/PD-L1 blockade benefit
por: Tomlins, Scott A., et al.
Publicado: (2023)

Elevated RIF1 participates in the epigenetic abnormalities of zygotes by regulating histone modifications on MuERV-L in obese mice
por: Huang, Jiliang, et al.
Publicado: (2022)

Validation of Immunotherapy Response Score as Predictive of Pan-solid Tumor Anti-PD-1/PD-L1 Benefit
por: Bulen, Benjamin J., et al.
Publicado: (2023)

Regulatory networks driving expression of genes critical for glioblastoma are controlled by the transcription factor c-Jun and the pre-existing epigenetic modifications
por: Roura, Adria-Jaume, et al.
Publicado: (2023)

Exploration of methylation-driven genes for monitoring and prognosis of patients with lung adenocarcinoma
por: Gao, Chundi, et al.
Publicado: (2018)

Survival-Associated Metabolic Genes and Risk Scoring System in HER2-Positive Breast Cancer
por: Gao, Chundi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_57eiguchfbqd4s4gdkr3reclh4