Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells

Neuregulin 4 (NRG4) has been described to improve metabolic disturbances linked to obesity status in rodent models. The findings in humans are controversial. We aimed to investigate circulating NRG4 in association with insulin action in humans and the possible mechanisms involved. Insulin sensitivit...

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Detalles Bibliográficos
Autores principales: Martínez, Cristina, Latorre, Jèssica, Ortega, Francisco, Arnoriaga-Rodríguez, María, Lluch, Aina, Oliveras-Cañellas, Núria, Díaz-Sáez, Francisco, Aragonés, Julian, Camps, Marta, Gumà, Anna, Ricart, Wifredo, Fernández-Real, José Manuel, Moreno-Navarrete, José María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521671/
https://www.ncbi.nlm.nih.gov/pubmed/36187779
http://dx.doi.org/10.3389/fphys.2022.950791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521671/
https://www.ncbi.nlm.nih.gov/pubmed/36187779
http://dx.doi.org/10.3389/fphys.2022.950791

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