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Synthesis and Bioactivity Evaluation of a Novel 1,2,4-Oxadiazole Derivative in vitro and in 3×Tg Mice

AIM: Alzheimer’s disease (AD) is the most common neurodegenerative disease whose patients suffered from cognitive impairments. In our study, a novel 1,2,4-Oxadiazole derivative wyc-7-20 was synthesized, which showed low cytotoxicity and potent neuroprotective effect at the cellular level. Improved c...

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Detalles Bibliográficos
Autores principales:	Luo, Zhuohui, Wang, Yongcheng, Pang, Shuo, Gao, Shan, Liu, Ning, Gao, Xiang, Zhang, Li, Qi, Xiaolong, Yang, Yajun, Zhang, Lianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521684/ https://www.ncbi.nlm.nih.gov/pubmed/36187086 http://dx.doi.org/10.2147/DDDT.S372750

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