Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii

Metabolic pathways underpin the growth and virulence of intracellular parasites and are therefore promising antiparasitic targets. The pentose phosphate pathway (PPP) is vital in most organisms, providing a reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) and ribose sugar for nucl...

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Detalles Bibliográficos
Autores principales: Xia, Ningbo, Guo, Xuefang, Guo, Qinghong, Gupta, Nishith, Ji, Nuo, Shen, Bang, Xiao, Lihua, Feng, Yaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521846/
https://www.ncbi.nlm.nih.gov/pubmed/36121870
http://dx.doi.org/10.1371/journal.ppat.1010864

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