Cargando…

Cek1 regulates ß(1,3)-glucan exposure through calcineurin effectors in Candida albicans

In order to successfully induce disease, the fungal pathogen Candida albicans regulates exposure of antigens like the cell wall polysaccharide ß(1,3)-glucan to the host immune system. C. albicans covers (masks) ß(1,3)-glucan with a layer of mannosylated glycoproteins, which aids in immune system eva...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wagner, Andrew S., Lumsdaine, Stephen W., Mangrum, Mikayla M., King, Ainsley E., Hancock, Trevor J., Sparer, Timothy E., Reynolds, Todd B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9521907/ https://www.ncbi.nlm.nih.gov/pubmed/36121853 http://dx.doi.org/10.1371/journal.pgen.1010405

Ejemplares similares

Activation of Cph1 causes ß(1,3)-glucan unmasking in Candida albicans and attenuates virulence in mice in a neutrophil-dependent manner
por: Wagner, Andrew S., et al.
Publicado: (2021)

Exposure of Candida albicans β (1,3)-glucan is promoted by activation of the Cek1 pathway
por: Chen, Tian, et al.
Publicado: (2019)

Caspofungin-induced β(1,3)-glucan exposure in Candida albicans is driven by increased chitin levels
por: Wagner, Andrew S., et al.
Publicado: (2023)

Lrg1 Regulates β (1,3)-Glucan Masking in Candida albicans through the Cek1 MAP Kinase Pathway
por: Chen, Tian, et al.
Publicado: (2019)

The Mkk2 MAPKK Regulates Cell Wall Biogenesis in Cooperation with the Cek1-Pathway in Candida albicans
por: Román, Elvira, et al.
Publicado: (2015)

When Is It Appropriate to Take Off the Mask? Signaling Pathways That Regulate ß(1,3)-Glucan Exposure in Candida albicans
por: Chen, Tian, et al.
Publicado: (2022)

Magnolol as a potent antifungal agent inhibits Candida albicans virulence factors via the PKC and Cek1 MAPK signaling pathways
por: Xie, Yufei, et al.
Publicado: (2022)

Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis
por: Puri, Sumant, et al.
Publicado: (2012)

Correction: Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis
por: Puri, Sumant, et al.
Publicado: (2013)

Draft Genome Sequences of Lacticaseibacillus rhamnosus cek-R1, Lacticaseibacillus paracasei cek-R2, and Lentilactobacillus otakiensis cek-R3, Isolated from a Beetroot Product
por: Kaszab, Eszter, et al.
Publicado: (2022)

Comparative analysis of calcineurin signaling between Candida dubliniensis and Candida albicans
por: Zhang, Jing, et al.
Publicado: (2012)

Nature of β-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation
por: de Assis, Leandro José, et al.
Publicado: (2022)

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin
por: Singh, Sheena D., et al.
Publicado: (2009)

Carvacrol Induces Candida albicans Apoptosis Associated With Ca(2+)/Calcineurin Pathway
por: Niu, Chao, et al.
Publicado: (2020)

Effects of beta-glucan in a mice model of vaginitis by candida albicans
por: De Farias Sales, Valéria Soraya, et al.
Publicado: (2015)

A computational model for regulation of nanoscale glucan exposure in Candida albicans
por: Wester, Michael J., et al.
Publicado: (2017)

Control of β-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence
por: Yang, Mengli, et al.
Publicado: (2022)

Hsp90 Is Involved in Apoptosis of Candida albicans by Regulating the Calcineurin-Caspase Apoptotic Pathway
por: Dai, BaoDi, et al.
Publicado: (2012)

Enhancing of Wound Healing in Burn Patients through Candida albicans β-Glucan
por: Abedini, Fateme, et al.
Publicado: (2022)

P029 Synergic effect of deferoxamine combined with fluconazole against fluconazole-resistant Candida Spp. through inhibited Cek1 MAPK signaling pathway
por: An, Lulu, et al.
Publicado: (2022)

Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans
por: da Silva Dantas, Alessandra, et al.
Publicado: (2021)

Accessibility and contribution to glucan masking of natural and genetically tagged versions of yeast wall protein 1 of Candida albicans
por: Granger, Bruce L.
Publicado: (2018)

Physical Interaction of Sodium Houttuyfonate With β-1,3-Glucan Evokes Candida albicans Cell Wall Remodeling
por: Da, Wenyue, et al.
Publicado: (2019)

Remasking of Candida albicans β-Glucan in Response to Environmental pH Is Regulated by Quorum Sensing
por: Cottier, Fabien, et al.
Publicado: (2019)

Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages
por: Leonhardt, Julia, et al.
Publicado: (2018)

Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation
por: Bain, Judith M., et al.
Publicado: (2014)

PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90
por: LaFayette, Shantelle L., et al.
Publicado: (2010)

Emodin Reduces the Activity of (1,3)-β-D-glucan Synthase from Candida albicans and Does Not Interact with Caspofungin
por: JANECZKO, MONIKA
Publicado: (2018)

Aucklandia lappa Causes Cell Wall Damage in Candida albicans by Reducing Chitin and (1,3)-β-D-Glucan
por: Lee, Heung-Shick, et al.
Publicado: (2020)

Glucan and glycogen exist as a covalently linked macromolecular complex in the cell wall of Candida albicans and other Candida species
por: Lowman, Douglas W., et al.
Publicado: (2021)

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment
por: Wheeler, Robert T., et al.
Publicado: (2008)

Revisiting the Vital Drivers and Mechanisms of β-Glucan Masking in Human Fungal Pathogen, Candida albicans
por: Hameed, Saif, et al.
Publicado: (2021)

Calcineurin Signaling and Membrane Lipid Homeostasis Regulates Iron Mediated MultiDrug Resistance Mechanisms in Candida albicans
por: Hameed, Saif, et al.
Publicado: (2011)

Calcium-Activated-Calcineurin Reduces the In Vitro and In Vivo Sensitivity of Fluconazole to Candida albicans via Rta2p
por: Jia, Yu, et al.
Publicado: (2012)

β-Glucan-Functionalized Nanoparticles Down-Modulate the Proinflammatory Response of Mononuclear Phagocytes Challenged with Candida albicans
por: Lima, Tânia, et al.
Publicado: (2022)

The Transient Receptor Potential Channel Yvc1 Deletion Recovers the Growth Defect of Calcineurin Mutant Under Endoplasmic Reticulum Stress in Candida albicans
por: Peng, Liping, et al.
Publicado: (2021)

Genomic and functional analyses unveil the response to hyphal wall stress in Candida albicans cells lacking β(1,3)-glucan remodeling
por: Degani, Genny, et al.
Publicado: (2016)

Developmental expression and distinctive tyrosine phosphorylation of the Eph-related receptor tyrosine kinase Cek9
Publicado: (1996)

A glycosylated Phr1 protein is induced by calcium stress and its expression is positively controlled by the calcium/calcineurin signaling transcription factor Crz1 in Candida albicans
por: Jiang, Linghuo, et al.
Publicado: (2023)

The Glucan-Remodeling Enzyme Phr1p and the Chitin Synthase Chs1p Cooperate to Maintain Proper Nuclear Segregation and Cell Integrity in Candida albicans
por: Degani, Genny, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ab6eji05u2ckdbgobhil0h8mvd