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Associations between cardiorespiratory fitness and diverticulitis in older adults

OBJECTIVES: Examine the independent and joint associations of cardiorespiratory fitness (CRF) and body mass index (BMI) with the prevalence of diverticulitis in older adults. METHODS: 476 older adults (61% Female; 71 ± 5 years) with no history of myocardial infarction, stroke, cancer, inflammatory b...

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Autores principales: Song, Bong Kil, Saavedra, Joey M., Lefferts, Elizabeth C., Brellenthin, Angelique G., Lee, Duck-chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522298/
https://www.ncbi.nlm.nih.gov/pubmed/36174031
http://dx.doi.org/10.1371/journal.pone.0275433
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author Song, Bong Kil
Saavedra, Joey M.
Lefferts, Elizabeth C.
Brellenthin, Angelique G.
Lee, Duck-chul
author_facet Song, Bong Kil
Saavedra, Joey M.
Lefferts, Elizabeth C.
Brellenthin, Angelique G.
Lee, Duck-chul
author_sort Song, Bong Kil
collection PubMed
description OBJECTIVES: Examine the independent and joint associations of cardiorespiratory fitness (CRF) and body mass index (BMI) with the prevalence of diverticulitis in older adults. METHODS: 476 older adults (61% Female; 71 ± 5 years) with no history of myocardial infarction, stroke, cancer, inflammatory bowel disease, or diabetes were included in this cross-sectional study. Diverticulitis cases were identified by self-reported physician diagnosis from the medical history questionnaire. Logistic regression was used to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) of the prevalence of diverticulitis by tertiles of CRF and BMI category. CRF and BMI were further dichotomized into either “unfit” (the lowest one-third of CRF), “fit” (the upper two-thirds of CRF), “overweight/obese” (BMI ≥25.0 kg/m(2)), or “normal-weight” (BMI <25.0 kg/m(2)) to investigate the joint association of CRF and BMI with diverticulitis. RESULTS: Thirty-five (7.4%) participants were identified as having diverticulitis. Compared with the lowest CRF tertile, the ORs (95% CIs) of diverticulitis were 0.52 (0.22–1.22) and 0.33 (0.12–0.94) in the middle and upper CRF tertiles, respectively, after adjusting for potential confounders. After further adjustment for BMI, the association was no longer significant with ORs (95% CIs) of 0.55 (0.23–1.33) and 0.37 (0.12–1.10) in middle and upper CRF tertiles, respectively. Compared with the normal-weight group, the ORs (95% CIs) of diverticulitis were 2.86 (1.05–7.79) and 2.98 (0.95–9.35) in the overweight and obese groups, respectively, after adjusting for possible confounders and CRF. Compared with the “unfit and overweight/obese” group in the joint analysis, the OR (95% CI) of diverticulitis was 0.16 (0.04–0.61) in the “fit and normal-weight” group. CONCLUSIONS: Older adults who maintain higher CRF and lower BMI may have significantly lower odds of diverticulitis, with the lowest odds found in the normal-weight and fit older adults.
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spelling pubmed-95222982022-09-30 Associations between cardiorespiratory fitness and diverticulitis in older adults Song, Bong Kil Saavedra, Joey M. Lefferts, Elizabeth C. Brellenthin, Angelique G. Lee, Duck-chul PLoS One Research Article OBJECTIVES: Examine the independent and joint associations of cardiorespiratory fitness (CRF) and body mass index (BMI) with the prevalence of diverticulitis in older adults. METHODS: 476 older adults (61% Female; 71 ± 5 years) with no history of myocardial infarction, stroke, cancer, inflammatory bowel disease, or diabetes were included in this cross-sectional study. Diverticulitis cases were identified by self-reported physician diagnosis from the medical history questionnaire. Logistic regression was used to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) of the prevalence of diverticulitis by tertiles of CRF and BMI category. CRF and BMI were further dichotomized into either “unfit” (the lowest one-third of CRF), “fit” (the upper two-thirds of CRF), “overweight/obese” (BMI ≥25.0 kg/m(2)), or “normal-weight” (BMI <25.0 kg/m(2)) to investigate the joint association of CRF and BMI with diverticulitis. RESULTS: Thirty-five (7.4%) participants were identified as having diverticulitis. Compared with the lowest CRF tertile, the ORs (95% CIs) of diverticulitis were 0.52 (0.22–1.22) and 0.33 (0.12–0.94) in the middle and upper CRF tertiles, respectively, after adjusting for potential confounders. After further adjustment for BMI, the association was no longer significant with ORs (95% CIs) of 0.55 (0.23–1.33) and 0.37 (0.12–1.10) in middle and upper CRF tertiles, respectively. Compared with the normal-weight group, the ORs (95% CIs) of diverticulitis were 2.86 (1.05–7.79) and 2.98 (0.95–9.35) in the overweight and obese groups, respectively, after adjusting for possible confounders and CRF. Compared with the “unfit and overweight/obese” group in the joint analysis, the OR (95% CI) of diverticulitis was 0.16 (0.04–0.61) in the “fit and normal-weight” group. CONCLUSIONS: Older adults who maintain higher CRF and lower BMI may have significantly lower odds of diverticulitis, with the lowest odds found in the normal-weight and fit older adults. Public Library of Science 2022-09-29 /pmc/articles/PMC9522298/ /pubmed/36174031 http://dx.doi.org/10.1371/journal.pone.0275433 Text en © 2022 Song et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Song, Bong Kil
Saavedra, Joey M.
Lefferts, Elizabeth C.
Brellenthin, Angelique G.
Lee, Duck-chul
Associations between cardiorespiratory fitness and diverticulitis in older adults
title Associations between cardiorespiratory fitness and diverticulitis in older adults
title_full Associations between cardiorespiratory fitness and diverticulitis in older adults
title_fullStr Associations between cardiorespiratory fitness and diverticulitis in older adults
title_full_unstemmed Associations between cardiorespiratory fitness and diverticulitis in older adults
title_short Associations between cardiorespiratory fitness and diverticulitis in older adults
title_sort associations between cardiorespiratory fitness and diverticulitis in older adults
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522298/
https://www.ncbi.nlm.nih.gov/pubmed/36174031
http://dx.doi.org/10.1371/journal.pone.0275433
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