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Coupling of microtubule bundles isolates them from local disruptions to set the structural stability of the anaphase spindle
Chromosome segregation requires load-bearing interactions across kinetochore fibers and antiparallel microtubule bundles, which constitute the spindle midzone. Mechanical properties of kinetochore fibers have been characterized during metaphase, when the mitotic spindle achieves steady state. Howeve...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522340/ https://www.ncbi.nlm.nih.gov/pubmed/36122237 http://dx.doi.org/10.1073/pnas.2204068119 |