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Human cone elongation responses can be explained by photoactivated cone opsin and membrane swelling and osmotic response to phosphate produced by RGS9-catalyzed GTPase
Human cone outer segment (COS) length changes in response to stimuli bleaching up to 99% of L- and M-cone opsins were measured with high resolution, phase-resolved optical coherence tomography (OCT). Responses comprised a fast phase (∼5 ms), during which COSs shrink, and two slower phases (1.5 s), d...
Autores principales: | Pandiyan, Vimal Prabhu, Nguyen, Phuong T., Pugh, Edward N., Sabesan, Ramkumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522364/ https://www.ncbi.nlm.nih.gov/pubmed/36122241 http://dx.doi.org/10.1073/pnas.2202485119 |
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