Optical clearing of the mouse skull

High spatial resolution imaging of the mouse brain through the intact skull is challenging because of the skull-induced aberration and scattering. The research group of Dan Zhu from Huazhong University of Science and Technology has developed a skull-clearing technique that provides a long-term (~ we...

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Autor principal: Xu, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522800/
https://www.ncbi.nlm.nih.gov/pubmed/36175405
http://dx.doi.org/10.1038/s41377-022-00989-0
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author Xu, Chris
author_facet Xu, Chris
author_sort Xu, Chris
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description High spatial resolution imaging of the mouse brain through the intact skull is challenging because of the skull-induced aberration and scattering. The research group of Dan Zhu from Huazhong University of Science and Technology has developed a skull-clearing technique that provides a long-term (~ weeks), stable, transparent window for high resolution optical imaging over a large field of view.
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spelling pubmed-95228002022-10-01 Optical clearing of the mouse skull Xu, Chris Light Sci Appl News & Views High spatial resolution imaging of the mouse brain through the intact skull is challenging because of the skull-induced aberration and scattering. The research group of Dan Zhu from Huazhong University of Science and Technology has developed a skull-clearing technique that provides a long-term (~ weeks), stable, transparent window for high resolution optical imaging over a large field of view. Nature Publishing Group UK 2022-09-29 /pmc/articles/PMC9522800/ /pubmed/36175405 http://dx.doi.org/10.1038/s41377-022-00989-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle News & Views
Xu, Chris
Optical clearing of the mouse skull
title Optical clearing of the mouse skull
title_full Optical clearing of the mouse skull
title_fullStr Optical clearing of the mouse skull
title_full_unstemmed Optical clearing of the mouse skull
title_short Optical clearing of the mouse skull
title_sort optical clearing of the mouse skull
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522800/
https://www.ncbi.nlm.nih.gov/pubmed/36175405
http://dx.doi.org/10.1038/s41377-022-00989-0
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