Current status of type 1 (IgG4-related) autoimmune pancreatitis

In 1995, Yoshida et al. proposed first the concept of “autoimmune pancreatitis” (AIP). Since then, AIP has been accepted as a new pancreatic inflammatory disease and is now divided two subtypes. Type 1 AIP affected immunoglobulin G4 (IgG4) and implicates the pancreatic manifestation of IgG4-related...

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Autores principales: Uchida, Kazushige, Okazaki, Kazuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522839/
https://www.ncbi.nlm.nih.gov/pubmed/35916965
http://dx.doi.org/10.1007/s00535-022-01891-7
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author Uchida, Kazushige
Okazaki, Kazuichi
author_facet Uchida, Kazushige
Okazaki, Kazuichi
author_sort Uchida, Kazushige
collection PubMed
description In 1995, Yoshida et al. proposed first the concept of “autoimmune pancreatitis” (AIP). Since then, AIP has been accepted as a new pancreatic inflammatory disease and is now divided two subtypes. Type 1 AIP affected immunoglobulin G4 (IgG4) and implicates the pancreatic manifestation of IgG4-related disease, while type 2 is characterized by neutrophil infiltration and granulocytic epithelial lesions (GEL). Recent research has clarified the clinical and pathophysiological aspects of type 1 AIP, which is more than type 2 among the Japanese population. However, many details remain unclear about the pathogenesis and progression of this disease. In this review, we discuss the current knowledge and recent advances relating to type 1 AIP.
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spelling pubmed-95228392022-10-01 Current status of type 1 (IgG4-related) autoimmune pancreatitis Uchida, Kazushige Okazaki, Kazuichi J Gastroenterol Review In 1995, Yoshida et al. proposed first the concept of “autoimmune pancreatitis” (AIP). Since then, AIP has been accepted as a new pancreatic inflammatory disease and is now divided two subtypes. Type 1 AIP affected immunoglobulin G4 (IgG4) and implicates the pancreatic manifestation of IgG4-related disease, while type 2 is characterized by neutrophil infiltration and granulocytic epithelial lesions (GEL). Recent research has clarified the clinical and pathophysiological aspects of type 1 AIP, which is more than type 2 among the Japanese population. However, many details remain unclear about the pathogenesis and progression of this disease. In this review, we discuss the current knowledge and recent advances relating to type 1 AIP. Springer Nature Singapore 2022-08-02 2022 /pmc/articles/PMC9522839/ /pubmed/35916965 http://dx.doi.org/10.1007/s00535-022-01891-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Uchida, Kazushige
Okazaki, Kazuichi
Current status of type 1 (IgG4-related) autoimmune pancreatitis
title Current status of type 1 (IgG4-related) autoimmune pancreatitis
title_full Current status of type 1 (IgG4-related) autoimmune pancreatitis
title_fullStr Current status of type 1 (IgG4-related) autoimmune pancreatitis
title_full_unstemmed Current status of type 1 (IgG4-related) autoimmune pancreatitis
title_short Current status of type 1 (IgG4-related) autoimmune pancreatitis
title_sort current status of type 1 (igg4-related) autoimmune pancreatitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522839/
https://www.ncbi.nlm.nih.gov/pubmed/35916965
http://dx.doi.org/10.1007/s00535-022-01891-7
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