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Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home

BACKGROUND: To reduce healthcare costs, it has become increasingly important to shorten the length of stay in acute stroke units. The goal of this study was to develop and externally validate a decision tree model applicable < 48 h poststroke for discharge home from an acute stroke unit with a sh...

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Autores principales: Veerbeek, Janne Marieke, Ottiger, Beatrice, Cazzoli, Dario, Vanbellingen, Tim, Nyffeler, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523004/
https://www.ncbi.nlm.nih.gov/pubmed/36188378
http://dx.doi.org/10.3389/fneur.2022.999595
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author Veerbeek, Janne Marieke
Ottiger, Beatrice
Cazzoli, Dario
Vanbellingen, Tim
Nyffeler, Thomas
author_facet Veerbeek, Janne Marieke
Ottiger, Beatrice
Cazzoli, Dario
Vanbellingen, Tim
Nyffeler, Thomas
author_sort Veerbeek, Janne Marieke
collection PubMed
description BACKGROUND: To reduce healthcare costs, it has become increasingly important to shorten the length of stay in acute stroke units. The goal of this study was to develop and externally validate a decision tree model applicable < 48 h poststroke for discharge home from an acute stroke unit with a short length of stay, and to assess the inappropriate home discharge rate. METHODS: A prospective study including two samples of stroke patients admitted to an acute stroke unit. The outcome was discharge home (yes/no). A classification and regression tree analysis was performed in Sample 1. The model's performance was tested in Sample 2. RESULTS: In total, 953 patients were included. The final decision tree included the patients' activities of daily living (ADL) performance <48 h poststroke, including motor function, cognition, and communication, and had an area under the curve (AUC) of 0.84 (95% confidence interval 0.76, 0.91). External validation resulted in an AUC of 0.74 (95% confidence interval 0.72, 0.77). None of the patients discharged home were re-admitted < 2 months after discharge to a hospital or admitted to a rehabilitation center for symptoms that had needed inpatient neurorehabilitation. CONCLUSIONS: The developed decision tree shows acceptable external validity in predicting discharge home in a heterogeneous sample of stroke patients, only based on the patient's actual ADL performance <48 h poststroke. Importantly, discharge was safe, i.e., no re-hospitalization was registered. The tree's application to speed up discharge planning should now be further evaluated.
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spelling pubmed-95230042022-10-01 Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home Veerbeek, Janne Marieke Ottiger, Beatrice Cazzoli, Dario Vanbellingen, Tim Nyffeler, Thomas Front Neurol Neurology BACKGROUND: To reduce healthcare costs, it has become increasingly important to shorten the length of stay in acute stroke units. The goal of this study was to develop and externally validate a decision tree model applicable < 48 h poststroke for discharge home from an acute stroke unit with a short length of stay, and to assess the inappropriate home discharge rate. METHODS: A prospective study including two samples of stroke patients admitted to an acute stroke unit. The outcome was discharge home (yes/no). A classification and regression tree analysis was performed in Sample 1. The model's performance was tested in Sample 2. RESULTS: In total, 953 patients were included. The final decision tree included the patients' activities of daily living (ADL) performance <48 h poststroke, including motor function, cognition, and communication, and had an area under the curve (AUC) of 0.84 (95% confidence interval 0.76, 0.91). External validation resulted in an AUC of 0.74 (95% confidence interval 0.72, 0.77). None of the patients discharged home were re-admitted < 2 months after discharge to a hospital or admitted to a rehabilitation center for symptoms that had needed inpatient neurorehabilitation. CONCLUSIONS: The developed decision tree shows acceptable external validity in predicting discharge home in a heterogeneous sample of stroke patients, only based on the patient's actual ADL performance <48 h poststroke. Importantly, discharge was safe, i.e., no re-hospitalization was registered. The tree's application to speed up discharge planning should now be further evaluated. Frontiers Media S.A. 2022-09-16 /pmc/articles/PMC9523004/ /pubmed/36188378 http://dx.doi.org/10.3389/fneur.2022.999595 Text en Copyright © 2022 Veerbeek, Ottiger, Cazzoli, Vanbellingen and Nyffeler. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Veerbeek, Janne Marieke
Ottiger, Beatrice
Cazzoli, Dario
Vanbellingen, Tim
Nyffeler, Thomas
Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
title Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
title_full Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
title_fullStr Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
title_full_unstemmed Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
title_short Speed up discharge planning at the acute stroke unit: A development and external validation study for the early prediction of discharge home
title_sort speed up discharge planning at the acute stroke unit: a development and external validation study for the early prediction of discharge home
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523004/
https://www.ncbi.nlm.nih.gov/pubmed/36188378
http://dx.doi.org/10.3389/fneur.2022.999595
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