MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis

Protein kinase A promotes beige adipogenesis downstream from β-adrenergic receptor signaling by phosphorylating proteins, including histone H3 lysine 9 (H3K9) demethylase JMJD1A. To ensure homeostasis, this process needs to be reversible however, this step is not well understood. We show that myosin...

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Detalles Bibliográficos
Autores principales: Takahashi, Hiroki, Yang, Ge, Yoneshiro, Takeshi, Abe, Yohei, Ito, Ryo, Yang, Chaoran, Nakazono, Junna, Okamoto-Katsuyama, Mayumi, Uchida, Aoi, Arai, Makoto, Jin, Hitomi, Choi, Hyunmi, Tumenjargal, Myagmar, Xie, Shiyu, Zhang, Ji, Sagae, Hina, Zhao, Yanan, Yamaguchi, Rei, Nomura, Yu, Shimizu, Yuichi, Yamada, Kaito, Yasuda, Satoshi, Kimura, Hiroshi, Tanaka, Toshiya, Wada, Youichiro, Kodama, Tatsuhiko, Aburatani, Hiroyuki, Zhu, Min-Sheng, Inagaki, Takeshi, Osborne, Timothy F., Kawamura, Takeshi, Ishihama, Yasushi, Matsumura, Yoshihiro, Sakai, Juro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523048/
https://www.ncbi.nlm.nih.gov/pubmed/36175407
http://dx.doi.org/10.1038/s41467-022-33363-0

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