Epistasis-Driven Evolution of the SARS-CoV-2 Secondary Structure

Epistasis is an evolutionary phenomenon whereby the fitness effect of a mutation depends on the genetic background in which it arises. A key source of epistasis in an RNA molecule is its secondary structure, which contains functionally important topological motifs held together by hydrogen bonds bet...

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Detalles Bibliográficos
Autores principales: Alemrajabi, Mahsa, Macias Calix, Ksenia, Assis, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523185/
https://www.ncbi.nlm.nih.gov/pubmed/36178491
http://dx.doi.org/10.1007/s00239-022-10073-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523185/
https://www.ncbi.nlm.nih.gov/pubmed/36178491
http://dx.doi.org/10.1007/s00239-022-10073-1

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