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Epistasis-Driven Evolution of the SARS-CoV-2 Secondary Structure
Epistasis is an evolutionary phenomenon whereby the fitness effect of a mutation depends on the genetic background in which it arises. A key source of epistasis in an RNA molecule is its secondary structure, which contains functionally important topological motifs held together by hydrogen bonds bet...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523185/ https://www.ncbi.nlm.nih.gov/pubmed/36178491 http://dx.doi.org/10.1007/s00239-022-10073-1 |