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Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia

BACKGROUND: In Malaysia, although diabetes accounts for more than 70% of all deaths, it is unclear how it relates to BMI and diabetic complications. This study aimed to investigate the prevalence of obesity and diabetic complications among diabetic patients in Malaysia. MATERIALS AND METHODS: A cros...

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Autores principales: Shaharuddin, Shazwani, Thuraisingam, Shobna, Daud, Noorul Aimi, Shafie, Sarah Diyana, Krishnan, Sunanthiny, Kow, Chia Siang, Appalasamy, Jamuna Rani, Ramachandram, Dinesh Sangarran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523188/
https://www.ncbi.nlm.nih.gov/pubmed/36196225
http://dx.doi.org/10.1007/s13410-022-01131-x
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author Shaharuddin, Shazwani
Thuraisingam, Shobna
Daud, Noorul Aimi
Shafie, Sarah Diyana
Krishnan, Sunanthiny
Kow, Chia Siang
Appalasamy, Jamuna Rani
Ramachandram, Dinesh Sangarran
author_facet Shaharuddin, Shazwani
Thuraisingam, Shobna
Daud, Noorul Aimi
Shafie, Sarah Diyana
Krishnan, Sunanthiny
Kow, Chia Siang
Appalasamy, Jamuna Rani
Ramachandram, Dinesh Sangarran
author_sort Shaharuddin, Shazwani
collection PubMed
description BACKGROUND: In Malaysia, although diabetes accounts for more than 70% of all deaths, it is unclear how it relates to BMI and diabetic complications. This study aimed to investigate the prevalence of obesity and diabetic complications among diabetic patients in Malaysia. MATERIALS AND METHODS: A cross-sectional study using an existing clinical registry was performed from 1 January 2020 to 31 December 2020 at Hospital Serdang, Malaysia. Adult patients with type 2 diabetes mellitus had their medical records examined for disease complications, as reported by the patient at first contact with the DMTAC pharmacist. RESULTS: The study comprised a total of 495 participants with an average HbA1c of 10.5%. About 91% (n = 451) of the 495 patients were obese/overweight. Around 37.8% (n = 187) of diabetic patients are between the ages of 50 and 59, and 59% (n = 292) have had diabetes for less than 10 years. A total of 8.5% (n = 42) and 9.7% (n = 48) consume alcohol and smoke, respectively. Around 29.9% (n = 148) had one other comorbidity (hypertension or dyslipidemia), and 63.4% (n = 314) had two comorbidities. Regarding the prevalence of complications, there were 18.9% (n = 94) who had myocardial infarction, 11.1% (n = 55) who had stroke, and 9% (n = 45) who had CKD. Age (adjusted OR = 1.03; 95% CI 1.00 to 1.07; p = 0.041) and hypertension (adjusted OR = 4.06; 95% CI 1.21 to 13.60; p = 0.023) were significantly related with the prevalence of complications in patients with diabetes. CONCLUSION: In our study, a BMI of more than 23 kg/m(2) (obese/overweight) does not seem to be associated with the prevalence of complications. Age and hypertension, on the other hand, appear to be strong risk predictors of the incidence of complications. With the understanding of the recent outlook on diabetes, it is recommended that public education on the targeted population should be encouraged to negate these complications. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13410-022-01131-x.
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spelling pubmed-95231882022-09-30 Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia Shaharuddin, Shazwani Thuraisingam, Shobna Daud, Noorul Aimi Shafie, Sarah Diyana Krishnan, Sunanthiny Kow, Chia Siang Appalasamy, Jamuna Rani Ramachandram, Dinesh Sangarran Int J Diabetes Dev Ctries Original Article BACKGROUND: In Malaysia, although diabetes accounts for more than 70% of all deaths, it is unclear how it relates to BMI and diabetic complications. This study aimed to investigate the prevalence of obesity and diabetic complications among diabetic patients in Malaysia. MATERIALS AND METHODS: A cross-sectional study using an existing clinical registry was performed from 1 January 2020 to 31 December 2020 at Hospital Serdang, Malaysia. Adult patients with type 2 diabetes mellitus had their medical records examined for disease complications, as reported by the patient at first contact with the DMTAC pharmacist. RESULTS: The study comprised a total of 495 participants with an average HbA1c of 10.5%. About 91% (n = 451) of the 495 patients were obese/overweight. Around 37.8% (n = 187) of diabetic patients are between the ages of 50 and 59, and 59% (n = 292) have had diabetes for less than 10 years. A total of 8.5% (n = 42) and 9.7% (n = 48) consume alcohol and smoke, respectively. Around 29.9% (n = 148) had one other comorbidity (hypertension or dyslipidemia), and 63.4% (n = 314) had two comorbidities. Regarding the prevalence of complications, there were 18.9% (n = 94) who had myocardial infarction, 11.1% (n = 55) who had stroke, and 9% (n = 45) who had CKD. Age (adjusted OR = 1.03; 95% CI 1.00 to 1.07; p = 0.041) and hypertension (adjusted OR = 4.06; 95% CI 1.21 to 13.60; p = 0.023) were significantly related with the prevalence of complications in patients with diabetes. CONCLUSION: In our study, a BMI of more than 23 kg/m(2) (obese/overweight) does not seem to be associated with the prevalence of complications. Age and hypertension, on the other hand, appear to be strong risk predictors of the incidence of complications. With the understanding of the recent outlook on diabetes, it is recommended that public education on the targeted population should be encouraged to negate these complications. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13410-022-01131-x. Springer India 2022-09-30 /pmc/articles/PMC9523188/ /pubmed/36196225 http://dx.doi.org/10.1007/s13410-022-01131-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Shaharuddin, Shazwani
Thuraisingam, Shobna
Daud, Noorul Aimi
Shafie, Sarah Diyana
Krishnan, Sunanthiny
Kow, Chia Siang
Appalasamy, Jamuna Rani
Ramachandram, Dinesh Sangarran
Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia
title Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia
title_full Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia
title_fullStr Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia
title_full_unstemmed Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia
title_short Investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in Malaysia
title_sort investigating the prevalence of diabetic complications in overweight/obese patients: a study in a tertiary hospital in malaysia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523188/
https://www.ncbi.nlm.nih.gov/pubmed/36196225
http://dx.doi.org/10.1007/s13410-022-01131-x
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