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Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery
The most common causes of perioperative hypersensitive reactions are neuromuscular blocking drugs, latex, and antibiotics, although there are other more emerging causative agents. Allergic reactions to Patent Blue V (PBV) dye have been reported. Most of them are mild and presented with blue colorati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523237/ https://www.ncbi.nlm.nih.gov/pubmed/36185281 http://dx.doi.org/10.3389/fonc.2022.979393 |
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author | Misir Šitum, Stanka Korečić Zrinjščak, Iva Pečvarac, Maja Šoštar, Andrea Žaja, Ana Tot, Tea |
author_facet | Misir Šitum, Stanka Korečić Zrinjščak, Iva Pečvarac, Maja Šoštar, Andrea Žaja, Ana Tot, Tea |
author_sort | Misir Šitum, Stanka |
collection | PubMed |
description | The most common causes of perioperative hypersensitive reactions are neuromuscular blocking drugs, latex, and antibiotics, although there are other more emerging causative agents. Allergic reactions to Patent Blue V (PBV) dye have been reported. Most of them are mild and presented with blue coloration of cutaneous plaque. The PBV dye is widely used in the identification of sentinel lymph nodes in patients with breast cancer and other malignancies. Here, we present a case of 33-year-old patient with carcinoma of the breast proposed for sentinel lymph node and skin-sparing mastectomy with severe, life-threatening anaphylaxis which occurred immediately after PBV dye was injected, with cardiopulmonal resuscitation and prolonged refractory hypotension. The patient was without previous exposure to PBV and signs of skin rash, erythema, or bronchospasm, making the diagnosis and management of such cases challenging. Skin tests were performed on all drugs used in premedication and induction of anesthesia and PBV showed positive at IDT of 1:10. Physicians must always think of possible adverse reaction to PBV and for the potential risk of anaphylactic reaction immediately after the dye is injected, during anesthesia and other procedures. |
format | Online Article Text |
id | pubmed-9523237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95232372022-10-01 Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery Misir Šitum, Stanka Korečić Zrinjščak, Iva Pečvarac, Maja Šoštar, Andrea Žaja, Ana Tot, Tea Front Oncol Oncology The most common causes of perioperative hypersensitive reactions are neuromuscular blocking drugs, latex, and antibiotics, although there are other more emerging causative agents. Allergic reactions to Patent Blue V (PBV) dye have been reported. Most of them are mild and presented with blue coloration of cutaneous plaque. The PBV dye is widely used in the identification of sentinel lymph nodes in patients with breast cancer and other malignancies. Here, we present a case of 33-year-old patient with carcinoma of the breast proposed for sentinel lymph node and skin-sparing mastectomy with severe, life-threatening anaphylaxis which occurred immediately after PBV dye was injected, with cardiopulmonal resuscitation and prolonged refractory hypotension. The patient was without previous exposure to PBV and signs of skin rash, erythema, or bronchospasm, making the diagnosis and management of such cases challenging. Skin tests were performed on all drugs used in premedication and induction of anesthesia and PBV showed positive at IDT of 1:10. Physicians must always think of possible adverse reaction to PBV and for the potential risk of anaphylactic reaction immediately after the dye is injected, during anesthesia and other procedures. Frontiers Media S.A. 2022-09-16 /pmc/articles/PMC9523237/ /pubmed/36185281 http://dx.doi.org/10.3389/fonc.2022.979393 Text en Copyright © 2022 Misir Šitum, Korečić Zrinjščak, Pečvarac, Šoštar, Žaja and Tot https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Misir Šitum, Stanka Korečić Zrinjščak, Iva Pečvarac, Maja Šoštar, Andrea Žaja, Ana Tot, Tea Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery |
title | Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery |
title_full | Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery |
title_fullStr | Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery |
title_full_unstemmed | Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery |
title_short | Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery |
title_sort | case report: atypical anaphylactic reaction to patent blue v dye during breast cancer surgery |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523237/ https://www.ncbi.nlm.nih.gov/pubmed/36185281 http://dx.doi.org/10.3389/fonc.2022.979393 |
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