PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype

Although PD-1 was shown to be a hallmark of T cells exhaustion, controversial studies have been reported on the role of PD-1 on NK cells. Here, we found by flow cytometry and single cell RNA sequencing analysis that PD-1 can be expressed on MHC class I-deficient tumor-infiltrating NK cells in vivo....

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Detalles Bibliográficos
Autores principales: Wagner, Arnika K., Kadri, Nadir, Tibbitt, Chris, van de Ven, Koen, Bagawath-Singh, Sunitha, Oliinyk, Denys, LeGresley, Eric, Campbell, Nicole, Trittel, Stephanie, Riese, Peggy, Ribacke, Ulf, Sandalova, Tatyana, Achour, Adnane, Kärre, Klas, Chambers, Benedict J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523278/
https://www.ncbi.nlm.nih.gov/pubmed/36185379
http://dx.doi.org/10.1016/j.isci.2022.105137

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