Suppression of endoplasmic reticulum stress-dependent autophagy enhances cynaropicrin-induced apoptosis via attenuation of the P62/Keap1/Nrf2 pathways in neuroblastoma

Autophagy has dual roles in cancer, resulting in cellular adaptation to promote either cell survival or cell death. Modulating autophagy can enhance the cytotoxicity of many chemotherapeutic and targeted drugs and is increasingly considered to be a promising cancer treatment approach. Cynaropicrin (...

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Detalles Bibliográficos
Autores principales: Yang, Randong, Ma, Shurong, Zhuo, Ran, Xu, Lingqi, Jia, Siqi, Yang, Pengcheng, Yao, Ye, Cao, Haibo, Ma, Liya, Pan, Jian, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523313/
https://www.ncbi.nlm.nih.gov/pubmed/36188599
http://dx.doi.org/10.3389/fphar.2022.977622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523313/
https://www.ncbi.nlm.nih.gov/pubmed/36188599
http://dx.doi.org/10.3389/fphar.2022.977622

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