Combining single-cell tracking and omics improves blood stem cell fate regulator identification

Molecular programs initiating cell fate divergence (CFD) are difficult to identify. Current approaches usually compare cells long after CFD initiation, therefore missing molecular changes at its start. Ideally, single cells that differ in their CFD molecular program but are otherwise identical are c...

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Detalles Bibliográficos
Autores principales: Wehling, A., Loeffler, D., Zhang, Y., Kull, T., Donato, C., Szczerba, B., Camargo Ortega, G., Lee, M., Moor, A., Göttgens, B., Aceto, N., Schroeder, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523371/
https://www.ncbi.nlm.nih.gov/pubmed/35820055
http://dx.doi.org/10.1182/blood.2022016880

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