Carbon dots conjugated to SN38 for improved colorectal anticancer therapy

Irinotecan (CTP-11) is one of the standard therapies for colorectal cancer (CRC). CTP-11 is enzymatically converted to the hydrophobic 7-ethyl-10-hydroxycamptothecin (SN38), a one hundred-fold more active metabolite. Conjugation of hydrophobic anticancer drugs to nanomaterials is a strategy to impro...

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Detalles Bibliográficos
Autores principales: Mattinzoli, Deborah, Cacioppo, Michele, Ikehata, Masami, Armelloni, Silvia, Alfieri, Carlo Maria, Castellano, Giuseppe, Barilani, Mario, Arcudi, Francesca, Messa, Piergiorgio, Prato, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523396/
https://www.ncbi.nlm.nih.gov/pubmed/36186846
http://dx.doi.org/10.1016/j.mtbio.2022.100286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523396/
https://www.ncbi.nlm.nih.gov/pubmed/36186846
http://dx.doi.org/10.1016/j.mtbio.2022.100286

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