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Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834)
Three norsesquiterpenoids, pathyspirolactones A (1) and B (2), and napalilactone (3), featuring a γ-spirolactone moiety, were isolated from the cultured octocoral Paralemnalia thyrsoides. The structures of 1–3 were determined by analyzing spectroscopic data, DP4+ computation, specific optical rotati...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523659/ https://www.ncbi.nlm.nih.gov/pubmed/36320270 http://dx.doi.org/10.1039/d2ra05015c |
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author | Phan, Gia Hung Hu, Hao-Chun Chang, Fang-Rong Wen, Zhi-Hong Chen, Jih-Jung Chung, Hsu-Ming Tsai, Yu-Chi Sung, Ping-Jyun |
author_facet | Phan, Gia Hung Hu, Hao-Chun Chang, Fang-Rong Wen, Zhi-Hong Chen, Jih-Jung Chung, Hsu-Ming Tsai, Yu-Chi Sung, Ping-Jyun |
author_sort | Phan, Gia Hung |
collection | PubMed |
description | Three norsesquiterpenoids, pathyspirolactones A (1) and B (2), and napalilactone (3), featuring a γ-spirolactone moiety, were isolated from the cultured octocoral Paralemnalia thyrsoides. The structures of 1–3 were determined by analyzing spectroscopic data, DP4+ computation, specific optical rotation, and X-ray diffraction. In addition, we explored the absolute configurations of pathyspirolactone A (1) and its conformation of the cyclohexane ring to resolve the stereochemical confusion of those of norsesquiterpenoid compounds. Furthermore, we proved that pathyspirolactone B (2) was the first bromine-containing norsesquiterpenoid reported from octocorals. |
format | Online Article Text |
id | pubmed-9523659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-95236592022-10-31 Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) Phan, Gia Hung Hu, Hao-Chun Chang, Fang-Rong Wen, Zhi-Hong Chen, Jih-Jung Chung, Hsu-Ming Tsai, Yu-Chi Sung, Ping-Jyun RSC Adv Chemistry Three norsesquiterpenoids, pathyspirolactones A (1) and B (2), and napalilactone (3), featuring a γ-spirolactone moiety, were isolated from the cultured octocoral Paralemnalia thyrsoides. The structures of 1–3 were determined by analyzing spectroscopic data, DP4+ computation, specific optical rotation, and X-ray diffraction. In addition, we explored the absolute configurations of pathyspirolactone A (1) and its conformation of the cyclohexane ring to resolve the stereochemical confusion of those of norsesquiterpenoid compounds. Furthermore, we proved that pathyspirolactone B (2) was the first bromine-containing norsesquiterpenoid reported from octocorals. The Royal Society of Chemistry 2022-09-30 /pmc/articles/PMC9523659/ /pubmed/36320270 http://dx.doi.org/10.1039/d2ra05015c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Phan, Gia Hung Hu, Hao-Chun Chang, Fang-Rong Wen, Zhi-Hong Chen, Jih-Jung Chung, Hsu-Ming Tsai, Yu-Chi Sung, Ping-Jyun Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) |
title | Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) |
title_full | Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) |
title_fullStr | Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) |
title_full_unstemmed | Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) |
title_short | Norsesquiterpenoids from the octocoral Paralemnalia thyrsoides (Ehrenberg 1834) |
title_sort | norsesquiterpenoids from the octocoral paralemnalia thyrsoides (ehrenberg 1834) |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523659/ https://www.ncbi.nlm.nih.gov/pubmed/36320270 http://dx.doi.org/10.1039/d2ra05015c |
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