Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases

Non-coding RNA is still one of the most popular fields in biology research. In recent years, people paid more attention to the roles of H19 in lung diseases, which expressed abnormally in various pathological process. Therefore, this review focus on the regulatory role of H19 in asthma, pulmonary ar...

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Autores principales: Xie, Jinghui, Hu, Yuedi, Sun, Dengdi, Liu, Changan, Li, Zegeng, Zhu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523668/
https://www.ncbi.nlm.nih.gov/pubmed/36188624
http://dx.doi.org/10.3389/fphar.2022.978151
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author Xie, Jinghui
Hu, Yuedi
Sun, Dengdi
Liu, Changan
Li, Zegeng
Zhu, Jie
author_facet Xie, Jinghui
Hu, Yuedi
Sun, Dengdi
Liu, Changan
Li, Zegeng
Zhu, Jie
author_sort Xie, Jinghui
collection PubMed
description Non-coding RNA is still one of the most popular fields in biology research. In recent years, people paid more attention to the roles of H19 in lung diseases, which expressed abnormally in various pathological process. Therefore, this review focus on the regulatory role of H19 in asthma, pulmonary arterial hypertension (PAH), idiopathic pulmonary fibrosis (IPF), lung injury, pneumonia, lung cancer, etc. And the potential therapeutic agents and molecular treatments of H19 are collected. The aim is to demonstrate its underlying mechanism in pulmonary diseases and to guide the basic research targeting H19 into clinical drug translation.
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spelling pubmed-95236682022-10-01 Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases Xie, Jinghui Hu, Yuedi Sun, Dengdi Liu, Changan Li, Zegeng Zhu, Jie Front Pharmacol Pharmacology Non-coding RNA is still one of the most popular fields in biology research. In recent years, people paid more attention to the roles of H19 in lung diseases, which expressed abnormally in various pathological process. Therefore, this review focus on the regulatory role of H19 in asthma, pulmonary arterial hypertension (PAH), idiopathic pulmonary fibrosis (IPF), lung injury, pneumonia, lung cancer, etc. And the potential therapeutic agents and molecular treatments of H19 are collected. The aim is to demonstrate its underlying mechanism in pulmonary diseases and to guide the basic research targeting H19 into clinical drug translation. Frontiers Media S.A. 2022-09-16 /pmc/articles/PMC9523668/ /pubmed/36188624 http://dx.doi.org/10.3389/fphar.2022.978151 Text en Copyright © 2022 Xie, Hu, Sun, Liu, Li and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Xie, Jinghui
Hu, Yuedi
Sun, Dengdi
Liu, Changan
Li, Zegeng
Zhu, Jie
Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
title Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
title_full Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
title_fullStr Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
title_full_unstemmed Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
title_short Targeting non-coding RNA H19: A potential therapeutic approach in pulmonary diseases
title_sort targeting non-coding rna h19: a potential therapeutic approach in pulmonary diseases
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523668/
https://www.ncbi.nlm.nih.gov/pubmed/36188624
http://dx.doi.org/10.3389/fphar.2022.978151
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