Inhibition of ROCK ameliorates pulmonary fibrosis by suppressing M2 macrophage polarisation through phosphorylation of STAT3

BACKGROUND: Emerging evidence provides mechanistic insights into the pathogenesis of pulmonary fibrosis (PF), and rare anti‐PF therapeutic method has promising effect in its treatment. Rho‐associated coiled‐coil kinases (ROCK) inhibition significantly ameliorates bleomycin‐induced PF and decreases m...

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Detalles Bibliográficos
Autores principales: Li, Qingfang, Cheng, Yuan, Zhang, Zhe, Bi, Zhenfei, Ma, Xuelei, Wei, Yuquan, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523675/
https://www.ncbi.nlm.nih.gov/pubmed/36178087
http://dx.doi.org/10.1002/ctm2.1036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523675/
https://www.ncbi.nlm.nih.gov/pubmed/36178087
http://dx.doi.org/10.1002/ctm2.1036

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