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Inhibition of ROCK ameliorates pulmonary fibrosis by suppressing M2 macrophage polarisation through phosphorylation of STAT3
BACKGROUND: Emerging evidence provides mechanistic insights into the pathogenesis of pulmonary fibrosis (PF), and rare anti‐PF therapeutic method has promising effect in its treatment. Rho‐associated coiled‐coil kinases (ROCK) inhibition significantly ameliorates bleomycin‐induced PF and decreases m...
Autores principales: | Li, Qingfang, Cheng, Yuan, Zhang, Zhe, Bi, Zhenfei, Ma, Xuelei, Wei, Yuquan, Wei, Xiawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523675/ https://www.ncbi.nlm.nih.gov/pubmed/36178087 http://dx.doi.org/10.1002/ctm2.1036 |
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