Current perspectives on irritable bowel syndrome: a narrative review

The pathophysiology of irritable bowel syndrome (IBS) has not yet been fully elucidated. We reviewed articles addressing IBS that have been published in the last 2 years and selected papers related to IBS pathophysiology and treatment. Studies of intestinal bacteria, low-grade mucosal inflammation,...

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Detalles Bibliográficos
Autores principales: Hojo, Mariko, Nagahara, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523849/
https://www.ncbi.nlm.nih.gov/pubmed/36171718
http://dx.doi.org/10.1177/03000605221126370
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author Hojo, Mariko
Nagahara, Akihito
author_facet Hojo, Mariko
Nagahara, Akihito
author_sort Hojo, Mariko
collection PubMed
description The pathophysiology of irritable bowel syndrome (IBS) has not yet been fully elucidated. We reviewed articles addressing IBS that have been published in the last 2 years and selected papers related to IBS pathophysiology and treatment. Studies of intestinal bacteria, low-grade mucosal inflammation, and increased mucosal permeability—factors involved in the pathophysiology of IBS—have been conducted. In addition, the involvement of intestinal bacteria in IBS pathology has been clarified; many studies of treatments related to intestinal bacteria have been reported. Moreover, several studies address the effect on IBS of antidepressants and psychotherapy through the brain–gut axis. The contents of these papers are described in this narrative review.
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spelling pubmed-95238492022-10-01 Current perspectives on irritable bowel syndrome: a narrative review Hojo, Mariko Nagahara, Akihito J Int Med Res Review The pathophysiology of irritable bowel syndrome (IBS) has not yet been fully elucidated. We reviewed articles addressing IBS that have been published in the last 2 years and selected papers related to IBS pathophysiology and treatment. Studies of intestinal bacteria, low-grade mucosal inflammation, and increased mucosal permeability—factors involved in the pathophysiology of IBS—have been conducted. In addition, the involvement of intestinal bacteria in IBS pathology has been clarified; many studies of treatments related to intestinal bacteria have been reported. Moreover, several studies address the effect on IBS of antidepressants and psychotherapy through the brain–gut axis. The contents of these papers are described in this narrative review. SAGE Publications 2022-09-28 /pmc/articles/PMC9523849/ /pubmed/36171718 http://dx.doi.org/10.1177/03000605221126370 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Hojo, Mariko
Nagahara, Akihito
Current perspectives on irritable bowel syndrome: a narrative review
title Current perspectives on irritable bowel syndrome: a narrative review
title_full Current perspectives on irritable bowel syndrome: a narrative review
title_fullStr Current perspectives on irritable bowel syndrome: a narrative review
title_full_unstemmed Current perspectives on irritable bowel syndrome: a narrative review
title_short Current perspectives on irritable bowel syndrome: a narrative review
title_sort current perspectives on irritable bowel syndrome: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523849/
https://www.ncbi.nlm.nih.gov/pubmed/36171718
http://dx.doi.org/10.1177/03000605221126370
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