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Breakdown of the central synapses in C9orf72-linked ALS/FTD

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease that leads to the death of motor and cortical neurons. The clinical manifestations of ALS are heterogenous, and efficacious treatments to significantly slow the progression of the disease are lacking. Cortical hype...

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Detalles Bibliográficos
Autores principales: Ghaffari, Layla T., Trotti, Davide, Haeusler, Aaron R., Jensen, Brigid K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9523884/
https://www.ncbi.nlm.nih.gov/pubmed/36187344
http://dx.doi.org/10.3389/fnmol.2022.1005112