Case of Glioblastoma Multiforme in the Left Temporoparietal Region of the Brain

Glioblastoma is one of the most frequent and malignant primary brain or spinal cord cancers. We present the case of a 48-year-old man diagnosed with a grade IV histology tumor, which is the most fatal according to WHO classification. Mutations in the p53, retinoblastoma protein (RB), receptor tyrosine kinase (RTK), rat sarcoma (RAS), and phosphoinositide 3-kinase (PI3K) signaling genes are frequently seen in glioblastoma. Radiation therapy, alkylating chemotherapy, and surgery are often used as glioblastoma treatments. O6-methylguanyl DNA methyltransferase (MGMT) promoter methylation predicts the effectiveness of alkylating chemotherapy with temozolomide, which directs the selection of first-line therapy in elderly patients. Glioblastoma goes unnoticed because of age-related factors, yet it is recognized that older people are more prone to getting it. The patient also had nausea, vomiting, and headaches. The disease's course was slowed while the patient's signs and symptoms were lessened by the treatment. The doctor checks reflexes, eyesight, hearing, coordination, and more. MRI is the most reliable tool for locating glial tumours. It is also possible to do additional diagnostic procedures like CT or positron emission tomography (PET) scans. A biopsy may also be carried out, depending on the circumstances and the location of the tumor. A biopsy's objective is to identify the cell's kind and the amount of its dissemination; specialized tests carried out by medical professionals and technicians reveal the prognosis and better treatment alternatives. The only treatments accessible now are surgery, chemotherapy, radiation, tumor treating fields therapy, targeted medication therapy, and palliative care. It is anticipated that there will be fewer fatalities in the future.