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Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer

BACKGROUND: As the increasing mortality and incidence of lung cancer (LC), there is an urgent need to discover novel treatment agent. In this study, we aimed to investigate the anti-LC effects of nitidine chloride (NC), a small molecular compound extracted from Chinese herbal medicine, while detaili...

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Detalles Bibliográficos
Autores principales:	Yu, Fei, Tan, Weidan, Chen, Zhiquan, Shen, Xiaoju, Mo, Xiaoxiang, Mo, Xiaocheng, He, Jingchuan, Deng, Zhihua, Wang, Jie, Luo, Zhuo, Yang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524076/ https://www.ncbi.nlm.nih.gov/pubmed/36175965 http://dx.doi.org/10.1186/s13020-022-00671-y

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