Cargando…

LAG3 blockade coordinates with microwave ablation to promote CD8(+) T cell-mediated anti-tumor immunity

BACKGROUND: The immune checkpoint inhibitors (ICIs) combined with other therapeutic strategies have shown exciting results in various malignancies, and ICIs have now become the gold standard for current cancer treatment. In several preclinical and clinical investigations, ablation coupled with immun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Dong, Chen, Yaping, Huang, Hao, Liu, Yingting, Chen, Junjun, Zhu, Dawei, Zheng, Xiao, Chen, Lujun, Jiang, Jingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524118/ https://www.ncbi.nlm.nih.gov/pubmed/36180876 http://dx.doi.org/10.1186/s12967-022-03646-7

Ejemplares similares

TIGIT Blockade Exerts Synergistic Effects on Microwave Ablation Against Cancer
por: Chen, Yaping, et al.
Publicado: (2022)

The CXCL10/CXCR3 Pathway Contributes to the Synergy of Thermal Ablation and PD-1 Blockade Therapy against Tumors
por: Xiao, Wenlu, et al.
Publicado: (2023)

Synergistic effect of CD47 blockade in combination with cordycepin treatment against cancer
por: Feng, Chen, et al.
Publicado: (2023)

CD226 identifies functional CD8(+)T cells in the tumor microenvironment and predicts a better outcome for human gastric cancer
por: Huang, Hao, et al.
Publicado: (2023)

Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells
por: Ma, Jiajia, et al.
Publicado: (2023)

Prognostic values of tissue-resident CD8(+)T cells in human hepatocellular carcinoma and intrahepatic cholangiocarcinoma
por: Chen, Lujun, et al.
Publicado: (2023)

PD-1 and LAG-3 blockade improve anti-tumor vaccine efficacy
por: Zahm, Christopher D., et al.
Publicado: (2021)

The methyltransferase METTL3 promotes tumorigenesis via mediating HHLA2 mRNA m6A modification in human renal cell carcinoma
por: Zhu, Dawei, et al.
Publicado: (2022)

CD38 identifies pre-activated CD8+ T cells which can be reinvigorated by anti-PD-1 blockade in human lung cancer
por: Wu, Pin, et al.
Publicado: (2021)

Localized RNA interference therapy to eliminate residual lung cancer after incomplete microwave ablation
por: Cao, Fei, et al.
Publicado: (2019)

Increased expression of METTL3 in pancreatic cancer tissues associates with poor survival of the patients
por: Li, Yuan, et al.
Publicado: (2022)

IL1R2 increases regulatory T cell population in the tumor microenvironment by enhancing MHC-II expression on cancer-associated fibroblasts
por: Chen, Lujun, et al.
Publicado: (2022)

CD8(+) T cells located in tertiary lymphoid structures are associated with improved prognosis in patients with gastric cancer
por: Li, Qing, et al.
Publicado: (2020)

CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
por: Zhang, Yuhan, et al.
Publicado: (2023)

Microwave ablation versus radiofrequency ablation for the treatment of pulmonary tumors
por: Shi, Feng, et al.
Publicado: (2017)

LAG-3 Blockade with Relatlimab (BMS-986016) Restores Anti-Leukemic Responses in Chronic Lymphocytic Leukemia
por: Sordo-Bahamonde, Christian, et al.
Publicado: (2021)

Simultaneous Genetic Ablation of PD-1, LAG-3, and TIM-3 in CD8 T Cells Delays Tumor Growth and Improves Survival Outcome
por: Ciraolo, Elisa, et al.
Publicado: (2022)

Blockade of LAG-3 Immune Checkpoint Combined With Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-viral CD8(+) T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease
por: Roy, Soumyabrata, et al.
Publicado: (2018)

Combining a nanoparticle-mediated immunoradiotherapy with dual blockade of LAG3 and TIGIT improves the treatment efficacy in anti-PD1 resistant lung cancer
por: Hu, Yun, et al.
Publicado: (2022)

Targeting CD96 overcomes PD-1 blockade resistance by enhancing CD8+ TIL function in cervical cancer
por: Wang, Yumeng, et al.
Publicado: (2022)

Microwave ablation versus radiofrequency ablation for treating spinal metastases
por: Yao, Yuming, et al.
Publicado: (2023)

Comparison of deep and moderate neuromuscular blockade in microwave ablation of liver tumours: a randomized-controlled clinical trial
por: Loh, Pui San, et al.
Publicado: (2021)

Autoreactive CD8(+) T cells are restrained by an exhaustion-like program that is maintained by LAG3
por: Grebinoski, Stephanie, et al.
Publicado: (2022)

Use of microwave ablation in the treatment of patients with multiple primary malignant tumors
por: Han, Yue, et al.
Publicado: (2017)

The influence of liposomal quercetin on liver damage induced by microwave ablation
por: Duan, Xuhua, et al.
Publicado: (2017)

Ablation of BATF Alleviates Transplant Rejection via Abrogating the Effector Differentiation and Memory Responses of CD8(+) T Cells
por: Li, Shuang, et al.
Publicado: (2022)

Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study
por: Min, Xin, et al.
Publicado: (2023)

CD8+ T Lymphocytes Immune Depletion and LAG-3 Overexpression in Hodgkin Lymphoma Tumor Microenvironment Exposed to Anti-PD-1 Immunotherapy
por: Michot, Jean-Marie, et al.
Publicado: (2021)

1.0 T open-configuration magnetic resonance-guided microwave ablation of pig livers in real time
por: Dong, Jun, et al.
Publicado: (2015)

Microwave ablation of breast pseudoaneurysm
por: Cai, Zhenyu, et al.
Publicado: (2022)

Oxysophocarpine suppresses hepatocellular carcinoma growth and sensitizes the therapeutic blockade of anti‐Lag‐3 via reducing FGL1 expression
por: Wang, Jianchu, et al.
Publicado: (2020)

Blockade of 6-phosphogluconate dehydrogenase generates CD8(+) effector T cells with enhanced anti-tumor function
por: Daneshmandi, Saeed, et al.
Publicado: (2021)

The Combination Strategy of Transarterial Chemoembolization and Radiofrequency Ablation or Microwave Ablation against Hepatocellular Carcinoma
por: Xu, Zhentian, et al.
Publicado: (2019)

The extent of metalloproteinase-mediated LAG3 cleavage limits the efficacy of PD1 blockade
por: Andrews, Lawrence P, et al.
Publicado: (2015)

Expression and prognostic value of PD-L1 and PD-L2 in ovarian cancer
por: Xue, Chunyan, et al.
Publicado: (2019)

Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8(+) T lymphocyte exhaustion
por: Ascione, Alessandro, et al.
Publicado: (2019)

A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8(+) T cell responses
por: Zhai, Wenjie, et al.
Publicado: (2020)

Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade
por: Banchereau, Romain, et al.
Publicado: (2021)

Safety and Feasibility of Microwave Ablation for Hepatocellular Carcinomas in the Elderly: A Systematic Review
por: Liang, Weiren, et al.
Publicado: (2022)

Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity
por: Nawaf, Maher G., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ng435lsvov8artsq0lc84ig3fg