Exploring the neurobiology of the premonitory phase of migraine preclinically – a role for hypothalamic kappa opioid receptors?

BACKGROUND: The migraine premonitory phase is characterized in part by increased thirst, urination and yawning. Imaging studies show that the hypothalamus is activated in the premonitory phase. Stress is a well know migraine initiation factor which was demonstrated to engage dynorphin/kappa opioid r...

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Detalles Bibliográficos
Autores principales: Kopruszinski, Caroline M., Vizin, Robson, Watanabe, Moe, Martinez, Ashley L., de Souza, Luiz Henrique Moreira, Dodick, David W., Porreca, Frank, Navratilova, Edita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524131/
https://www.ncbi.nlm.nih.gov/pubmed/36175828
http://dx.doi.org/10.1186/s10194-022-01497-7

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