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WZB117 enhanced the anti-tumor effect of apatinib against melanoma via blocking STAT3/PKM2 axis

Background: Melanoma is the most lethal skin malignant tumor with a short survival once stepping into the metastatic status and poses a therapeutic challenge. Apatinib (a tyrosine kinase inhibitor) is a promising antiangiogenic agent for the treatment of metastatic melanoma. However, antiangiogenic...

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Detalles Bibliográficos
Autores principales:	Zhang, Ren-Shu, Li, Zhi-Ke, Liu, Jie, Deng, Yao-Tiao, Jiang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9524253/ https://www.ncbi.nlm.nih.gov/pubmed/36188586 http://dx.doi.org/10.3389/fphar.2022.976117

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